Advanced diagnosis of coronary atherosclerosis has been elucidated in this book with supportive researches and information. Coronary artery disease (CAD) and its effects are most significant mortality reasons in the advanced as well as rising nations. To avoid hard end-points, early judgment and adequate treatment play important role. Newly developed diagnosis tests which are biomarkers of irritation, cell adhesion, cell activation and imaging methods offer to get the finest outcome in the recognition and classification of calcified or uncalcified atherosclerotic plaques. In spite of spectacular advancements in the imaging techniques, coronary catheterization is still regularly used. Ever since the first cardiac catheterization was performed in 1800s, day by day historical improvements and the workings of cardiac catheterization methods, associated risks of coronary angiography, and also, preventions and cure of probable issues have been analyzed in this book. Another important issue is the exposure of patients and practitioners to radiation during coronary angiography and scintigraphy and that is why radiation dose reduction techniques and general principles of radiation protection have also been presented in this book.