In this book, Chapter One shows the new challenges for managers in relation to the management of operations permeate aspects of development and/or aggregation of services, stronger link with market strategies, flexible and cost competitive systems, intensive information technology and automation. In Chapter Two, the authors show the methodological process to the identification and the verification of the critical success factors of the TCUs survey variables by means of statistical analysis. Chapter Three argues that against the background of hyper-complexity the usefulness of all mainstream approaches of change management has to be scrutinized. Chapter Four is focused on a theoretical framework motivated by the influence of TMT composition on strategic change and firm performance. Chapter Five examines the importance and the implementation of critical success factors (CSFs) of quality management systems (QMSs). Chapter Six presents the concepts of critical success factors of projects and their applications in various sectors.