Advances in DNA Damage and Repair: Oxygen Radical Effects, Cellular Protection, and Biological Consequences: NATO Science Series A:, cartea 302
Editat de Miral Dizdaroglu, Ali Esat Karakayaen Limba Engleză Hardback – 28 feb 1999
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Specificații
ISBN-13: 9780306460425
ISBN-10: 0306460424
Pagini: 511
Ilustrații: XI, 511 p.
Dimensiuni: 155 x 235 x 29 mm
Greutate: 0.9 kg
Ediția:1999
Editura: Springer Us
Colecția Springer
Seria NATO Science Series A:
Locul publicării:New York, NY, United States
ISBN-10: 0306460424
Pagini: 511
Ilustrații: XI, 511 p.
Dimensiuni: 155 x 235 x 29 mm
Greutate: 0.9 kg
Ediția:1999
Editura: Springer Us
Colecția Springer
Seria NATO Science Series A:
Locul publicării:New York, NY, United States
Public țintă
ResearchCuprins
1. Mapping Reactive Oxygen-Induced DNA Damage at Nucleotide Resolution.- 2. Application of Oxidative DNA Damage Measurements to Study Antioxidant Actions of Dietary Components.- 3. DNA Repair and Transcription in Premature Aging Syndromes.- 4. Excision Repair of 8-Oxoguanine in Eukaryotes: The Oggl Proteins.- 5. Oxidative Base Damage to DNA: Recent Mechanistic Aspects, Measurement and Repair.- 6. Roles of AP Endonucleases in Repair and Genetic Stability.- 7. Mechanisms of Oxidative DNA Damage; Lesions and Their Measurement.- 8. Drosophila Ribosomal Protein S3 Contains N-Glycosylase, Abasic Site, and Deoxyribophosphodiesterase DNA Repair Activities.- 9. Bypass of DNA Damage by RNA Polymerases: Implications for DNA Repair and Transcriptional Mutagenesis.- 10. The Current Status of Nucleotide Excision Repair in the Yeast Saccharomyces cerevisiae.- 11. Physiological Chemistry of Superoxide and Nitric Oxide Interactions: Implications in DNA Damage and Repair.- 12. Recognition and Excision of Bases from Oxidatively Damaged DNA by Fpg, Oggl, and MutY Proteins.- 13. DNA Repair as a Susceptibility Factor in Chronic Diseases in Human Populations.- 14. Transcription-Coupled DNA Repair: Which Lesions? Which Diseases?.- 15. Genotoxicity Tests: Application to Occupational Exposure as Biomarkers.- 16. Studies on Oxidative Mechanisms of Metal-Induced Carcinogenesis: Recent Developments.- 17. Mechanism of Action of Escherichia coli Formamidopyrimidine N-Glycosylase and Endonuclease V.- 18. Human Uracil-DNA Glycosylase: Gene Structure, Regulation, and Structural Basis for Catalysis.- 19. Repair of DNA Damaged by Free Radicals.- 20. DNA Lesions Generated in Vivo by Reactive Oxygen Species, Their Accumulation and Repair.- 21. DNA Damage by Iron and Hydrogen Peroxide.- 22. Measurement of Oxidative Damage to DNA Nucleobases in Vivo: Interpretation of Nuclear Levels and Urinary Excretion of Repair Products.- 23. Effects of Vitamin E Supplementation on in Vivo Oxidative DNA Damage.- 24. Repair of Oxidative DNA Damage and Aging: Central Role of AP-Endonuclease.- 25. Action of Antioxidants against Oxidative Stress.- 26. 8-Hydroxyguanine, DNA Adduct Formed by Oxygen Radicals: From Its Discovery to Current Studies on Its Involvement in Mutagenesis and Repair.- 27. DNA Damage Induced by Reactive Nitrogen Species.- 28. Modification of Ionizing Radiation Damage to Cellular DNA by Factors Affecting Chromatin Structure: Effects of Histone Deacetylase Inhibitors Trichostatin A and Sodium Butyrate.- 29. Estimation of Free Radical Induced DNA Base Damages in Cancerous- and HIV Infected Patients and in Healthy Subjects.- 30. p53 Tumor Suppressor Gene: Its Role in DNA Damage Response and Cancer.- 31. Molecular Mechanism of Nucleotide Excision Repair in Mammalian Cells.- 32. Detection of 8-Hydroxy-2’-Deoxyguanosine by a Monoclonal Antibody N45.1 and Its Application.- 33. Mechanistic Studies of Radiation-Induced DNA Damage.- 34. Processing and Consequences of Oxidative DNA Base Lesions.- 35. Ionizing Radiation Damage to DNA: A Challenge to Repair Systems.- Abstracts.- Participants.- Participants Photo.- Author Index.