According to a U.S. census study, about 1 in 5 U.S. residents cope with special needs. Parents and caregivers who are faced with this issue of special needs experience feelings of denial, confusion, guilt, anger and hopelessness. Caring for special needs individuals is not an easy task, but it is possible. It is a journey that brings out the best in any individual who has chosen to embrace that challenge. The author gives the details of her journey as a mother of two boys with multiple special needs and illustrates the strategies that she has used to deal with the daily struggles that life presents her as she mothers her two children. She explains how acceptance of this challenge has led to it being the greatest blessing of her life. Against the odds is an inspiring narrative that will provide guidance for parents and caregivers who are searching for new tools and insights into how to raise children with special needs and for those who want to gain a deeper understanding of this important subject.