Cantitate/Preț
Produs

Algae-Based Biopharmaceuticals

Autor Sergio Rosales-Mendoza
en Limba Engleză Paperback – 30 mai 2018
This book constitutes a key reference on the use of algae in the biopharmaceuticals production field; providing an updated outlook on the achievements accomplished thus far and transmitting a prospective view for this biotechnological application.
This book provides a detailed description of the technology as well as an updated outlook of the strides achieved thus far in the field of algae-based biopharmaceuticals. Algae constitute attractive expression hosts for the production of recombinant proteins with medical applications. Among the features that make them attractive candidates are: low cost, fast growth, wide biosynthetic capacity, and absence of human pathogens; which constitute substantial advantages with respect to bacterial and mammalian systems. 
First, the features of algae as convenient hosts for the production of BFs are analyzed in terms of production costs, biosynthetic capacity, and safety (Chapter 1). Second, the genetic engineering tools for algae-species are described. Nuclear and chloroplast-based expression approaches are analyzed and compared in terms of biosynthetic advantages, gene expression complexity, and DNA transfer approaches (Chapter 2). In the following sections, chapters 3 to 7, the state of the art on producing distinct types of BFs in algae species is presented. Although this book is mainly focused on BFs, considering that the production of compounds with health-promoting properties are achieved using genetically-engineered algae strains, chapter 8 deals with nutraceuticals. In the ninth chapter, the developments reported thus far are placed in perspective and challenges for the field are discussed. Critical future prospects comprise the following: optimizing large-scale production in bioreactors, implementing glycoengineering approaches, optimizing nuclear expression, exploring new approaches for oral delivery, and implementing regulatory frameworks to accomplish technology transferand regulatory approval of algae-made BFs.


Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 54989 lei  38-44 zile
  Springer International Publishing – 30 mai 2018 54989 lei  38-44 zile
Hardback (1) 62952 lei  3-5 săpt.
  Springer International Publishing – 31 mai 2016 62952 lei  3-5 săpt.

Preț: 54989 lei

Preț vechi: 68735 lei
-20% Nou

Puncte Express: 825

Preț estimativ în valută:
10524 10931$ 8742£

Carte tipărită la comandă

Livrare economică 30 ianuarie-05 februarie 25

Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9783319812298
ISBN-10: 3319812297
Pagini: 166
Ilustrații: X, 166 p. 47 illus., 22 illus. in color.
Dimensiuni: 155 x 235 mm
Ediția:Softcover reprint of the original 1st ed. 2016
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

The Biopharmaceuticals Field and Algae as Expression Hosts.- Genetic Engineering Approaches for Algae.- Algae-made Vaccines Targeting Human Diseases.- Algae-made Vaccines Targeting Animal Pathogens.- Algae-made Antibodies and Immunotoxins.- Algae-made Cytokines and Growth Factors.- Other Biopharmaceuticals Produced in Algae.- Algae-made Nutraceuticals.- Perspectives for the Algae-made Biopharmaceuticals Field.

Notă biografică

Dr. Sergio Rosales-Mendoza is professor of Biotechnology and has worked in the area of biopharmaceuticals produced in low‐cost platforms for the past 10 years. Over his career, Dr. Rosales-Mendoza has published several scientific refereed articles in international high‐impact scientific journals. 

Textul de pe ultima copertă

This book constitutes a key reference on the use of algae in the BFs production field; providing an updated outlook on the achievements accomplished thus far and transmitting a prospective view for this biotechnological application.
This book provides a detailed description of the technology as well as an updated outlook of the strides achieved thus far in the field of algae-based biopharmaceuticals. Algae constitute attractive expression hosts for the production of recombinant proteins with medical applications. Among the features that make them attractive candidates are: low cost, fast growth, wide biosynthetic capacity, and absence of human pathogens; which constitute substantial advantages with respect to bacterial and mammalian systems.

First, the features of algae as convenient hosts for the production of BFs are analyzed in terms of production costs, biosynthetic capacity, and safety (Chapter 1). Second, the genetic engineering tools for algae-speciesare described. Nuclear and chloroplast-based expression approaches are analyzed and compared in terms of biosynthetic advantages, gene expression complexity, and DNA transfer approaches (Chapter 2). In the following sections, chapters 3 to 7, the state of the art on producing distinct types of BFs in algae species is presented. Although this book is mainly focused on BFs, considering that the production of compounds with health-promoting properties are achieved using genetically-engineered algae strains, chapter 8 deals with nutraceuticals. In the ninth chapter, the developments reported thus far are placed in perspective and challenges for the field are discussed. Critical future prospects comprise the following: optimizing large-scale production in bioreactors, implementing glycoengineering approaches, optimizing nuclear expression, exploring new approaches for oral delivery, and implementing regulatory frameworks to accomplish technology transfer and regulatory approval of algae-made BFs.



Caracteristici

Provides a detailed description of biopharmaceuticals production as well as an overview of the field of algae-made biopharmaceuticals Analyzes and compares chloroplast expression approaches in terms of gene expression schemes, yields, and post-translational modifications The first comprehensive book in this field