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Amyloid Protein Precursor in Development, Aging and Alzheimer’s Disease: Research and Perspectives in Alzheimer's Disease

Editat de C.L. Masters, K. Beyreuther, Marc Trillet
en Limba Engleză Paperback – 29 aug 2012

Din seria Research and Perspectives in Alzheimer's Disease

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Specificații

ISBN-13: 9783662011379
ISBN-10: 3662011379
Pagini: 280
Ilustrații: XX, 257 p. 44 illus., 10 illus. in color.
Dimensiuni: 155 x 235 x 15 mm
Greutate: 0.4 kg
Ediția:Softcover reprint of the original 1st ed. 1994
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Research and Perspectives in Alzheimer's Disease

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

Strategic Thoughts on the Alzheimer’s Disease Amyloid Protein Precursor: The Way Forward.- Drosophila Appl Gene and APPL Protein: A Model System to Study the Function of the APP Protein Family.- Amyloid ?A4 of Alzheimer’s Disease: Structural Requirements for Folding and Aggregation.- Production of Amyloid ? Protein from Normal and Mutated Amyloid ² Protein Precursors.- Mechanism of Cerebral Amyloidosis in Alzheimer’s Disease.- Effects of Fragments of the ?-Amyloid Protein on Hippocampal Neurons in Young and Aged Rats: An Electrophysiological Study.- The Role of the Extracellular Matrix in Regulating the Function of the Amyloid Protein Precursor of Alzheimer’s Disease.- Studies of the Amyloid Precursor Protein (APP) in Brain: Regulation of APP-Ligand Binding.- The Biological Function of Amyloid ?/A4 Protein Precursor.- Processing of Alzheimer A?-Amyloid Precursor Protein: Cell Biology, Regulation, and Role in Alzheimer’s Disease.- Studies of APP Biology: Analysis of APP Secretion and Characterization of an APP Homologue, APLP2.- Transmembrane APP is Distributed into Two Pools and Associated with Polymerized Cytoskeleton.- Isolation and Characterisation of Novel Metalloproteases from Embryonic Mouse Hippocampus.- A Transgenic Mouse Model of Alzheimer’s Disease.- Amyloid in Alzheimer’s Disease and Animal Models.- The Roles of Zinc and Copper in the Function and Metabolism of the Amyloid Protein Precursor Superfamily.- The Diverse Molecular Nature of Inherited Alzheimer’s Disease.- Genetic Variability and Alzheimer’s Disease.- Genetic Defects in Early Onset Alzheimer’s Disease and Related Disorders.- APP Gene Mutations in Familial Alzheimer’s Disease in Sweden.- Aging, Energy and Alzheimer’s Disease.- Molecular Biology and Genetics of HumanPrion Diseases and PrP Amyloid Plaque Formation.