An introduction to genetic epidemiology: Health and Society
Autor Lyle J. Palmeren Limba Engleză Paperback – 30 mai 2011
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Specificații
ISBN-13: 9781861348975
ISBN-10: 1861348975
Pagini: 256
Ilustrații: black & white tables, diagrams, figures, charts, graphs
Dimensiuni: 172 x 240 x 13 mm
Greutate: 0.41 kg
Editura: Bristol University Press
Seria Health and Society
Locul publicării:United Kingdom
ISBN-10: 1861348975
Pagini: 256
Ilustrații: black & white tables, diagrams, figures, charts, graphs
Dimensiuni: 172 x 240 x 13 mm
Greutate: 0.41 kg
Editura: Bristol University Press
Seria Health and Society
Locul publicării:United Kingdom
Recenzii
This book should be incredibly useful to students and researchers at all levels in genetic epidemiology. For students it offers an eminently readable and accessible foundation, and for researchers, a superb source to fill in missing pieces in our knowledge. Ezra Susser, Professor of Epidemiology and Psychiatry, Mailman School of Public Health, Columbia University, and New York State Psychiatric Institute
This is a sobering must-read for anyone who wishes to know how genetic epidemiology may change how we understand, treat or prevent human disease. Robert Elston, Case Western Reserve University School of Medicine
Notă biografică
Lyle J. Palmer, Western Australian Institute for Medical Research, University of Western Australia, Paul R. Burton, Department of Health Sciences and Department of Genetics, University of Leicester and George Davey Smith, Department of Social Medicine, University of Bristol
Cuprins
List of tables, figures and boxes
Notes on contributors
Acknowledgements
Introduction
Lyle J. Palmer, Paul R. Burton, and George Davey Smith
1. Key concepts in genetic epidemiology
Paul R. Burton, Martin D. Tobin, and John L. Hopper
2. Genetic linkage studies
M. Dawn Teare and Jennifer H. Barrett
3. Genetic association studies
Heather J. Cordell and David G. Clayton
4. Mapping complex disease genes using linkage disequilibrium and genome-wide association scans
Lyle J. Palmer, Nicholas J. Timpson, David M. Evans, George Davey Smith, and Lon R. Cardon
5. A question of standards: what makes a good genetic association study?
Andrew T. Hattersley and Mark I. McCarthy
6. Biobanks and biobank harmonisation
Paul R. Burton, Isabel Fortier, Mylene Deschênes, Anna Hansell, and Lyle J. Palmer
7. Population health aspects of genetic epidemiology: genomic profiling, personalised medicine, and Mendelian randomisation
George Davey Smith, Shah Ebrahim, Sarah Lewis, and Lyle J. Palmer
Glossary
Index
Notes on contributors
Acknowledgements
Introduction
Lyle J. Palmer, Paul R. Burton, and George Davey Smith
1. Key concepts in genetic epidemiology
Paul R. Burton, Martin D. Tobin, and John L. Hopper
2. Genetic linkage studies
M. Dawn Teare and Jennifer H. Barrett
3. Genetic association studies
Heather J. Cordell and David G. Clayton
4. Mapping complex disease genes using linkage disequilibrium and genome-wide association scans
Lyle J. Palmer, Nicholas J. Timpson, David M. Evans, George Davey Smith, and Lon R. Cardon
5. A question of standards: what makes a good genetic association study?
Andrew T. Hattersley and Mark I. McCarthy
6. Biobanks and biobank harmonisation
Paul R. Burton, Isabel Fortier, Mylene Deschênes, Anna Hansell, and Lyle J. Palmer
7. Population health aspects of genetic epidemiology: genomic profiling, personalised medicine, and Mendelian randomisation
George Davey Smith, Shah Ebrahim, Sarah Lewis, and Lyle J. Palmer
Glossary
Index