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Angiogenesis Modulations in Health and Disease: Practical Applications of Pro- and Anti-angiogenesis Targets

Editat de Shaker A. Mousa, Paul J. Davis
en Limba Engleză Paperback – 23 iun 2015
 This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in research and development of angiogenesis modulating targets.
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Specificații

ISBN-13: 9789401785150
ISBN-10: 9401785155
Pagini: 216
Ilustrații: X, 206 p.
Dimensiuni: 155 x 235 x 17 mm
Greutate: 0.31 kg
Ediția:2013
Editura: SPRINGER NETHERLANDS
Colecția Springer
Locul publicării:Dordrecht, Netherlands

Public țintă

Graduate

Cuprins

Preface.- Angiogenesis assays: an appraisal of current techniques.- Survey of pro-angiogenesis strategies.- Angiogenesis modulation by arachidonic acid – derived lipids: positive and negative regulators of angiogenesis.- Pro-angiogenic activity of thyroid hormone analogues: Mechanisms, physiology and clinical prospects.- Actions of steroids and peptide hormones on angiogenesis.- Role of non-neuronal nicotinic acetylcholine receptors in angiogenesis modulation.-  Catecholamine neurotransmitters: an angiogenic switch in the tumor microenvironment.- Impact of nanotechnology on therapeutic angiogenesis.- Survey of anti-angiogenesis strategies.- Tetraiodothyroacetic acid (tetrac), nanotetrac and anti-Angiogenesis.- Integrin antagonists and angiogenesis.- Anti-angiogenesis therapy as an adjunct to chemotherapy in oncology.- Anti-vegf strategies in ocular angiogenesis- mediated disorders, with special emphasis on age-related macular degeneration.- Application of nanotechnology to targeting tumor angiogenesis for therapeutic benefit.- Biomarkers of response and resistance to anti-angiogenic treatment.- Speculations on new directions in which angiogenesis may proceed. Index.

Textul de pe ultima copertă

 This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in research and development of angiogenesis modulating targets.

Caracteristici

In-depth explanations of pro-angiogenesis and anti-angiogenesis targets and their evaluation methods Clinical implications of pro-angiogenesis and anti-angiogenesis strategies Dedicated chapter on the impact of nanotechnology, stem cells, and biotechnology in angiogenesis control Detailed description of thyroid hormone analogues’ physiology and clinical potential Discussion of the future in the clinic for controlling angiogenesis