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Animal Models of Neurological Disease, II: Metabolic Encephalopathies and Epilepsies: Neuromethods, cartea 22

Editat de Alan A. Boulton, Glen B. Baker, Roger F. Butterworth
en Limba Engleză Hardback – 29 iul 1992
to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neuropsychiatric disorders. Because of increasing public concern over the ethical treatment of animals in research, we felt it incumbent upon us to include this general preface to these volumes in order to indicate why we think further - search using animals is necessary and why animal models of psychiatric disorders, in particular, are so important. We recognize that animals should only be used when suitable alternatives are not available. We think it self-e- dent, however, that humans can only be experimented upon in severely proscribed circumstances and alternative pro- dures using cell or tissue culture are inadequate in any models requiring assessments of behavioral change or of complex in vivo processes. However, when the distress, discomfort, or pain to the animals outweighs the anticipated gains for human welfare, then the research is not ethical and should not be carried out. It is imperative that each individual researcher examine his/her own research from a critical moral standpoint - fore engaging in it, taking into consideration the animals’ welfare as well as the anticipated gains. Furthermore, once a decision to proceed with research is made, it is the researcher’s responsibility to ensure that the animals’ w- fare is of prime concern in terms of appropriate housing, feeding, and maximum reduction of any uncomfortable or distressing effects of the experimental conditions, and that these conditions undergo frequent formalized monitoring.
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Specificații

ISBN-13: 9780896032118
ISBN-10: 0896032116
Pagini: 373
Ilustrații: XVIII, 373 p.
Dimensiuni: 155 x 235 x 25 mm
Greutate: 0.75 kg
Ediția:1992
Editura: Humana Press Inc.
Colecția Humana
Seria Neuromethods

Locul publicării:Totowa, NJ, United States

Public țintă

Research

Cuprins

Experimental Models of Human Stroke.- Animal Models of Brain Hypoxia.- Animal Models of the Wernicke-Korsakoff Syndrome.- Chemically Induced Models of Seizures.- The Kindling Model of Epilepsy.- Genetically Based Animal Models of Seizures.- Animal Models of Hepatic Encephalopathies.- Animal Models for Reye’s Syndrome.- Animal Models of Niacin-Nicotinamide Deficiency.- Pyridoxine Deficiency.- Animal Models of Hereditary Hyperammonemias.

Recenzii

These books go out of their way to be helpful. Most chapters introduce the animal models against the background of the human (i.e., clinical) context and conclude with a brief summary. Detailed experimental protocols and useful tabulations abound. Descriptions are exhaustive.-Trends in Neurosciences