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Animal Models of Speech and Language Disorders

Editat de Santosh A. Helekar
en Limba Engleză Paperback – 22 aug 2016
Basic research over the last decade or two has uncovered similarities between speech, especially its sensori-motor aspects, and vocal communication in several non-human species. The most comprehensive studies so far have been conducted in songbirds. Songbirds offer us a model system to study the interactions between developmental or genetic predispositions and tutor-dependent influences, on the learning of vocal communication. Songbird research has elucidated cellular and molecular mechanisms underlying learning and production of vocal patterns, perception of vocal sounds, vocal motor control and vocal neuromotor plasticity. More recently, the entire genome of the songbird zebra finch has been sequenced. These discoveries, along with the identification of several genes implicated in familial human speech and language disorders, have made it possible to look for analogues of speech and language dysfunction in zebra finches, at least at the perceptual and sensori-motor levels. Two approaches in particular have led us closer to the development of animal models of human speech conditions, namely developmental stuttering and a familial verbal dyspraxia associated with a mutation in the gene for the transcription factor FoxP2. Work on other animals that show developmental sensori-motor learning of vocal sounds used for communication have also shown significant progress, leading to the possibility of development of models of speech and language dysfunction in them. Among mammals, the principal ones include dolphins and whales. In non-human primates, while vocal learning per se is not very prominent, investigations on their communicative abilities have thrown some light on the rudiments of language. These considerations make the publication of a book focused on animal models of speech and language disorders, detailing the overall investigative approach of neurobehavioral studies in animals capable of vocal communication and learned vocalizations, a much-needed and worthwhile project. It would serve as a unifying review of research in this new multidisciplinary frontier, spanning the molecular to the behavioral, for clinicians and researchers, as well as a teaching resource for advanced speech pathology and neuroscience students. This book will also be the first of its kind.
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Specificații

ISBN-13: 9781493942732
ISBN-10: 1493942735
Pagini: 308
Ilustrații: X, 295 p. 58 illus., 43 illus. in color.
Dimensiuni: 155 x 235 x 16 mm
Greutate: 0.44 kg
Ediția:Softcover reprint of the original 1st ed. 2013
Editura: Springer
Colecția Springer
Locul publicării:New York, NY, United States

Cuprins

Preface.- Section I – Introduction to Speech and Language Disorders.- Chapter 1. Neurology of Speech and Language Disorders.- Chapter 2. Genetic Pathways Implicated in Speech and Language.- Section II – Songbird Model of Vocal Learning.- Chapter 3. Time Scales of Vocal Learning in Songbirds.- Chapter 4. The Songbird Auditory System.- Chapter 5. Prospective: How the Zebra finch Genome Strengthens Brain-Behavior Connections in Songbird Models of Learned Vocalization.- Chapter 6. The Molecular Convergence of Birdsong and Speech.- Chapter 7. Stuttered Birdsong.- Section III – Mammalian Models of Vocal Communication.- Chapter 8. The Repertoire of Communication Calls Emitted by Bats and the Ways the Calls are Processed in the Inferior Colliculus.- Chapter 9. Language Parallels in New World Primates.- Chapter 10. Apes, Language and the Brain.
 

Textul de pe ultima copertă

Animal Models of Speech and Language Disorders is arguably the first book that integrates several decades of research on the neuroscience and genetics of speech and language with behavioral, systems, cellular and molecular neurobiological studies on animal communication to create a synthesis of ideas with potential translational value in neurology, neurolinguistics and speech science.
 
Speech and language dysfunctions plague a large segment of today’s young and old alike because, besides being primary afflictions, they are also an integral part of the complex symptomatology of most of the common neurological and neurodevelopmental disorders, such as stroke, dementia, intellectual disability and autism. It is therefore essential that biomedical research be focused on understanding their neurobiological and genetic bases in order to have the chance of developing rational approaches to treating them. By weaving together findings from diverse disciplines in the comparative biology of vocal communication in songbirds, bats, New World monkeys and the great apes, with the applied and translational perspective in mind, this book attempts to create awareness among researchers and students about the strengths of the comparative and evolutionary approach to the scientific understanding of speech and language, and to addressing intractable clinical problems affecting higher brain functions.
 
Animal Models of Speech and Language Disorders will be highly instructive to researchers, clinicians, advanced speech pathology and neuroscience students, and all those who are interested in the current state of knowledge in the basic and applied aspects of speech and language.

Caracteristici

Details the overall investigative approach of neurobehavioral studies in animals capable of vocal communication and learned vocalizations
A unifying review of research in this new multidisciplinary frontier
Spans the molecular to the behavioral, for clinicians and researchers
Includes supplementary material: sn.pub/extras