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Antibiotics as Anti-Inflammatory and Immunomodulatory Agents: Progress in Inflammation Research

Editat de Bruce K. Rubin, Jun Tamaoki
en Limba Engleză Hardback – 22 noi 2004
Although the potential for immunomodulation has been recognized for many years there has been an explosion of data in this field with relevance especially to the treatment of chronic airway diseases. Most of the work in this field has been conducted by Japanese investigators but in the last decade there has been a body of work outside of Japan that supports and enhances these findings. The book covers basic research like effects on bacteria, anti-inflammatory and mucoregulatory effects, but also clinical results with up-to-date information for the use of such medications to potentially treat diseases as diverse as chronic airway diseases, arthritis, inflammatory bowel disease, and cancer.
The volume is intended for pulmonary physicians, researchers in inflammation research, and pharmaceutical companies interested in the development of such agents. It provides background information for the clinician as well as in depth exploration of cutting edge science.
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Specificații

ISBN-13: 9783764359256
ISBN-10: 3764359250
Pagini: 276
Ilustrații: XIII, 276 p.
Dimensiuni: 170 x 244 x 22 mm
Greutate: 0.67 kg
Ediția:2005
Editura: Birkhäuser Basel
Colecția Birkhäuser
Seria Progress in Inflammation Research

Locul publicării:Basel, Switzerland

Public țintă

Research

Cuprins

Basic research.- Effects of antibiotics on Pseudomonas aeruginosa virulence factors and quorum-sensing system.- Antibiotics, inflammation and its resolution: An overview.- The cytoprotective interactions of antibiotics with human ciliated airway epithelium.- Chemotaxis.- Cytokines.- Antibacterial agents and the oxidative burst.- Immune system.- Macrolides and mucus production.- Ion channel regulation.- Clinical results.- The use of macrolides for treatment of diffuse panbronchiolitis.- Macrolides in cystic fibrosis.- Macrolides and upper airway/sinus disease.- Benefits of macrolides in the treatment of asthma.- Roles of macrolides in treatment of lung injury.- Macrolides and cancer, arthritis and IBD.- Anti-inflammatory properties of antibiotics other than macrolides.

Recenzii

This concise and well-illustrated monograph contains much information of value to clinical immunologists and microbiologists engaged in research on the management and treatment of infectious diseases."
(Clinical Infectious Diseases)

Caracteristici

International authorship Covers basic research and clinical results