Antimicrobial Pharmacodynamics in Theory and Clinical Practice
Editat de Charles H. Nightingale, Paul G. Ambrose, George L. Drusano, Takeo Murakawaen Limba Engleză Hardback – 15 iun 2007
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Specificații
ISBN-13: 9780824729257
ISBN-10: 0824729250
Pagini: 534
Ilustrații: 143 b/w images, 67 tables and 2 halftones
Dimensiuni: 152 x 229 x 31 mm
Greutate: 0.82 kg
Ediția:2Revizuită
Editura: CRC Press
Colecția CRC Press
ISBN-10: 0824729250
Pagini: 534
Ilustrații: 143 b/w images, 67 tables and 2 halftones
Dimensiuni: 152 x 229 x 31 mm
Greutate: 0.82 kg
Ediția:2Revizuită
Editura: CRC Press
Colecția CRC Press
Public țintă
Academic and Professional Practice & DevelopmentCuprins
Introduction. Pharmacodynamics of Antimicrobials: General Concepts and Applications Impact of Pharmacodynamics on Breakpoint Selection for Susceptibility Testing. Non-Clinical Models of Infection. In Vitro Antibiotic Pharmacokinetic Models. Animal Models of Infection for the Study of Antibiotic Pharmacodynamics. The Predictive Value of Laboratory Tests for Efficacy of Antibiotic Combination Therapy. Antibacterial Agents. Beta-Lactam Antibiotics. Aminoglycoside Antibiotics. Quinolones. Glycopeptides. Macrolide, Azalide and Ketolides. Metronidazole, and Clindamycin. Streptogramins, Oxazolididones. Tetracyclines. Antiviral Agents. Nucleoside Reverse Transcriptase Inhibitors. Protease Inhibitors. Hepatitis B and C. Antifungal Agents. Amphotericin. Azoles. Gulcan Synthase Inhibitors. Antimalarial Agents. Anti-Malarials. Pharmacodynamics in Drug Development. Human Pharmacodynamics of Anti-Infectives: Determination from Clinical Trial Data. Pharmacodynamics in Global Bridging Studies. Toxicodynamics. Pharmacodynamics and Resistance. Antibacterial Resistance. Application of PK-PD to Clinical and Formulary Decisions. Basic Pharmacoeconomics. Utilizing Pharmacodynamics and Pharmacoeconomics in Clinical and Formulary Decision Making.
Notă biografică
Nightingale, Charles H.; Ambrose, Paul G.; Drusano, George L.; Murakawa, Takeo
Descriere
Taking readers from the research laboratory to the bedside, this Second Edition compiles essential information on the pharmacodynamics of all major classes of the antimicrobial armamentarium including penicillins, cephalosposorins, cephamycins, carbapenems, monobactams, aminoglycosides, quinolones, macrolides, antifungals, antivirals, and emerging agents currently in development. Written by experienced professionals in the field, this guide uses an abundance of examples to depict methods to apply pharmacodynamic concepts to everyday clinical practice.