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Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis: Comprehensive Analytical Chemistry, cartea 71

Sandra Perez, Peter Eichhorn, Damia Barcelo
en Limba Engleză Hardback – iun 2016
Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis deals with the use of high-resolution mass spectrometry (MS) in the analysis of small organic molecules. Over the past few years, time-of-flight (ToF) and Orbitrap MS have both experienced tremendous growth in a great number of analytical sectors and are now well established in many laboratories where high requirements are placed on analytical performance.
This book gives a head-to-head comparison of these two technologies that compete directly with each other. As users with hands-on experience in both techniques, the authors provide a balanced description of the strengths and weaknesses of both techniques. In the vast majority of cases, ToF-MS and Orbitrap-MS have been used for qualitative purposes, mainly identification of discrete molecular entities such as drug metabolites or transformation products of environmental contaminants.
This paradigm is now changing as quantitative capabilities are increasingly being explored, as are non-target approaches for unbiased broad-scope screening. In view of the continuous innovation of high-resolution MS instrument manufacturers in designing and developing more powerful machines, technological advances in both hardware and software are considerable, with many novel applications.
This book summarizes and analyzes these trends. The compilation of selected examples from diverse analytical fields will allow the readers to discover not only the potential of high-resolution MS in their sector, but also shows advances in other fields that rely on hi-res MS.


  • Provides comprehensive coverage of applications of time-of-flight and orbitrap mass spectrometry in environmental, food, doping, and forensic analysis
  • Explores a variety of specialized techniques, giving a balanced description of the strengths and weaknesses of each
  • Presents a general overview of imaging techniques within analysis
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Specificații

ISBN-13: 9780444635723
ISBN-10: 0444635726
Pagini: 524
Dimensiuni: 152 x 229 x 30 mm
Greutate: 1 kg
Editura: ELSEVIER SCIENCE
Seria Comprehensive Analytical Chemistry


Public țintă

Specialised analytical chemists and users of imaging analysis techniques in various disciplines including material sciences, medicine, biology, art and archaeology

Cuprins

Instrumentation
  1. Orbitrap Mass Spectrometry: Evolution and ApplicabilityClaudia P.B. Martins, Maciej Bromirski, Mari C. Prieto Conaway and Alexander A. Makarov
  2. Advances in Time of Flight Mass SpectrometryJohn C. Fjeldsted
  3. Ambient Ionization-High Resolution Mass Spectrometry: Environmental, Food, Forensic and Doping Analysis.Raquel Seró, Óscar Núñez and Encarnación Moyano
    Target Analysis, Identification, and Suspect Screening
  4. High Resolution Mass Spectrometry in Doping ControlGeorgina Balcells, Oscar J. Pozo and Rosa Ventura
  5. Application of LC-Time of Flight and Orbitrap-MS/MS for Pesticide Residues in Fruits and VegetablesŁukasz Rajski, María del Mar Gómez Ramos and Amadeo R. Fernández-Alba
  6. Identification of Sildenafil Designer Analogues Found in Dietary SupplementsXiaowei Ge, Chee-Leong Kee, Yun Zeng and Min-Yong Low
  7. High-Resolution Mass Spectrometry in Metabolite IdentificationMayurbhai Kathadbhai Ladumor, Shristy Tiwari, Amol Patil, Krishna Bhavsar, Shalu Jhajra, Bhagwat Prasad and Saranjit Singh
  8. LC-TOF-MS for the Identification of Environmental Metabolites and Degradation ProductsImma Ferrer, Jeffrey H. Writer, Olya S. Keen, Yaal Lester, Juan A. Padilla-Sánchez, Carolina Fernández-Ramos and E. Michael Thurman
  9. Application of Orbitrap Mass Spectrometry for the Identification of Transformation Products of Trace Organic Contaminants Formed in the EnvironmentCarsten Prasse and Thomas A. Ternes
  10. High Resolution-Mass Spectrometry Identification of Micropollutants Transformation Products Produced During Water Disinfection with Chlorine and Related ChemicalsIria González-Mariño, Inmaculada Carpinteiro, Rosario Rodil, Isaac Rodríguez and José Benito Quintana
  11. Discovery of New Emerging DBPs by High Resolution Mass SpectrometrySusan D. Richardson and Cristina Postigo
  12. Suspect Screening of Pharmaceuticals and Related Bioactive Compounds, Their Metabolites and Their Transformation Products in the Aquatic Environment, Biota and Humans Using LC-HR-MS TechniquesJaume Aceña, Nubia Heuett, Piero Gardinali and Sandra Pérez
    Non-Target Analysis
  13. Non-Target Analysis of Environmental Samples Based on Liquid Chromatography Coupled to High Resolution Mass Spectrometry (LC-HRMS)Pablo Gago-Ferrero, Emma L. Schymanski, Juliane Hollender and Nikolaos S. Thomaidis
  14. Non-Targeted Analysis of Persistent Organic Pollutants by Mass Spectrometry and GC×GCXavier Ortiz Almirall, Miren Pena Abaurrea, Karl J. Jobst and Eric J. Reiner
  15. High Resolution Mass Spectrometry in the Effect-Directed Analysis of Water ResourcesMartin Krauss
    Conclusions
  16. Conclusions and Future Directions Peter Eichhorn and Sandra Pérez