Arthritis Research: Volume 1: Methods and Protocols: Methods in Molecular Medicine, cartea 135
Editat de Andrew P. Copeen Limba Engleză Hardback – 6 iul 2007
In Volume 1, authors discuss synovial joint morphology, histopathology, and immunohistochemistry, cartilage matrix and bone biology, and cell trafficking, migration and invasion. Volume 2 is broken up into sections that cover immunobiology and T cells, animal models of arthritis, and applications of new technologies, such as Differential Display Reverse Transcription-Polymerase Chain Reaction (DDRT-PCR), to define novel therapeutic targets. Both volumes combine to produce a concise set of protocols condensing decades of experience and expertise.
Arthritis Research: Methods and Protocols will be a valuable tool for basic research investigators, clinician scientists, pathologists, immunologists, and biochemists looking to stay current in their fields.
Toate formatele și edițiile | Preț | Express |
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Paperback (2) | 786.50 lei 6-8 săpt. | |
Humana Press Inc. – 10 noi 2010 | 786.50 lei 6-8 săpt. | |
Humana Press Inc. – 10 noi 2010 | 788.14 lei 6-8 săpt. | |
Hardback (2) | 985.50 lei 38-44 zile | |
Humana Press Inc. – 6 iul 2007 | 985.50 lei 38-44 zile | |
Humana Press Inc. – 6 iul 2007 | 1112.17 lei 6-8 săpt. |
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Specificații
ISBN-13: 9781588293442
ISBN-10: 1588293440
Pagini: 476
Ilustrații: XX, 446 p. 114 illus., 15 illus. in color.
Dimensiuni: 152 x 229 x 35 mm
Greutate: 0.86 kg
Ediția:2007
Editura: Humana Press Inc.
Colecția Humana
Seria Methods in Molecular Medicine
Locul publicării:Totowa, NJ, United States
ISBN-10: 1588293440
Pagini: 476
Ilustrații: XX, 446 p. 114 illus., 15 illus. in color.
Dimensiuni: 152 x 229 x 35 mm
Greutate: 0.86 kg
Ediția:2007
Editura: Humana Press Inc.
Colecția Humana
Seria Methods in Molecular Medicine
Locul publicării:Totowa, NJ, United States
Public țintă
ResearchCuprins
Synovial Joint Morphology, Histopathology, and Immunohistochemistry.- Imaging Inflamed Synovial Joints.- Arthroscopy as a Research Tool.- Immunohistochemistry of the Inflamed Synovium.- In Situ Hybridization of Synovial Tissue.- Subtractive Hybridization.- Laser Capture as a Tool for Analysis of Gene Expression in Inflamed Synovium.- Preparation of Mononuclear Cells from Synovial Tissue.- Quantitative Image Analysis of Synovial Tissue.- Cartilage Matrix and Bone Biology.- Cartilage Histomorphometry.- Image Analysis of Aggrecan Degradation in Articular Cartilage With Formalin-Fixed Samples.- In situ Detection of Cell Death in Articular Cartilage.- Measurement of Glycosaminoglycan Release from Cartilage Explants.- Assessment of Collagenase Activity in Cartilage.- Assessment of Gelatinase Expression and Activity in Articular Cartilage.- Analyses of MT1-MMP Activity in Cells.- Analysis of TIMP Expression and Activity.- Bone Histomorphometry in Arthritis Models.- Generation of Osteoclasts In Vitro, and Assay of Osteoclast Activity.- Cell Trafficking, Migration, and Invasion.- Isolation and Analysis of Large and Small Vessel Endothelial Cells.- Analysis of Flow-Based Adhesion In Vitro.- Analysis of Leukocyte Recruitment in Synovial Microcirculation by Intravital Microscopy.- Angiogenesis in Arthritis.- Analysis of Inflammatory Leukocyte and Endothelial Chemotactic Activity.- Acquisition, Culture, and Phenotyping of Synovial Fibroblasts.- Genotyping of Synovial Fibroblasts.- Gene Transfer to Synovial Fibroblast.- In Vitro Matrigel Fibroblast Invasion Assay.- Culture and Analysis of Circulating Fibrocytes.
Recenzii
From the reviews:
"...offers a comprehensive reference for the analysis of tissues relevant to arthritis research in brief chapters that emphasize how various analyses are performed. What separates this series from other references in this area is its ability to be brief but thorough in the discussion of technically challenging methods." -Doody's Book Review, Weighted Numerical Score:95 - 4 Stars
"This multiauthored … compendium of arthritis research methods and protocols provides pertinent practical information for the bench researcher as well as for the interested clinician. … It is a worthwhile reference to have in the research laboratory … . I enthusiastically recommend … and believe this publication would have broad appeal to the rheumatologic community and to those in related specialties. … I congratulate the authors on developing an excellent compendium of arthritis research … ." (Robert J. Quinet, JAMA, April, 2008)
"Arthritis Research: Methods and Protocols forms part of a book series on Methods in Molecular Medicine by Humana Press. … Overall the books are extremely useful as both a practical guide and a reference text and are easy to understand. We would recommend the books to anyone with an interest in rheumatology research – basic scientists, clinicians and students … ." (Leonie Taams and Hayley Evans, Immunology News, August, 2008)
"...offers a comprehensive reference for the analysis of tissues relevant to arthritis research in brief chapters that emphasize how various analyses are performed. What separates this series from other references in this area is its ability to be brief but thorough in the discussion of technically challenging methods." -Doody's Book Review, Weighted Numerical Score:95 - 4 Stars
"This multiauthored … compendium of arthritis research methods and protocols provides pertinent practical information for the bench researcher as well as for the interested clinician. … It is a worthwhile reference to have in the research laboratory … . I enthusiastically recommend … and believe this publication would have broad appeal to the rheumatologic community and to those in related specialties. … I congratulate the authors on developing an excellent compendium of arthritis research … ." (Robert J. Quinet, JAMA, April, 2008)
"Arthritis Research: Methods and Protocols forms part of a book series on Methods in Molecular Medicine by Humana Press. … Overall the books are extremely useful as both a practical guide and a reference text and are easy to understand. We would recommend the books to anyone with an interest in rheumatology research – basic scientists, clinicians and students … ." (Leonie Taams and Hayley Evans, Immunology News, August, 2008)
Caracteristici
Broad range of topics covering many aspects of rheumatic disease In-depth studies of cutting-edge technology Robust tools for translational research Contributions from leaders in their fields