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Autophagy and Senescence in Cancer Therapy de Paul B. Fisher

Autophagy and Senescence in Cancer Therapy: Advances in Cancer Research, cartea 150

Paul B. Fisher, David A. Gewirtz
en Limba Engleză Hardback – 14 apr 2021
Advances in Cancer Research, Volume 150, the latest release in this ongoing series, covers the relationship(s) between autophagy and senescence, how they are defined, and the influence of these cellular responses on tumor dormancy and disease recurrence. Specific sections in this new release include Autophagy and senescence, converging roles in pathophysiology, Cellular senescence and tumor promotion: role of the unfolded protein response, autophagy and senescence in cancer stem cells, Targeting the stress support network regulated by autophagy and senescence for cancer treatment, Autophagy and PTEN in DNA damage-induced senescence, mTOR as a senescence manipulation target: A forked road, and more.

  • Addresses the relationship between autophagy and senescence in cancer therapy
  • Covers autophagy and senescence in tumor dormancy
  • Explores autophagy and senescence in disease recurrence
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Specificații

ISBN-13: 9780128241585
ISBN-10: 0128241586
Pagini: 382
Dimensiuni: 152 x 229 mm
Greutate: 0.68 kg
Editura: ELSEVIER SCIENCE
Seria Advances in Cancer Research

Public țintă

The volume is appropriate for scientists and physician-scientists who are interested in how tumor cells respond to cancer therapeutics and potentially evade the cell killing effects of standard of care therapy.

Cuprins

1.Autophagy and senescence in cancer therapy
Nipa H. Patel, Sarah Bloukh, Enas Alwohosh, Ahmad Alhesa, Tareq Saleh, and David A. Gewirtz
2. Targeting the stress support network regulated by autophagy and senescence for cancer treatment
Jaejin Kim, Yeonghyeon Lee, Kyeonghwan Roh, Mi-Sung Kim, and Chanhee Kang
3. Autophagy and senescence, converging roles in pathophysiology as seen through mouse models
Andrew R.J. Young, Liam D. Cassidy, and Masashi Narita
4. Autophagy and senescence: Insights from normal and cancer stem cells
Sarmistha Talukdar, Swadesh K. Das, Luni Emdad, and Paul B. Fisher
5. The role of autophagy in escaping therapy-induced polyploidy/senescence
Magdalena Dudkowska, Karolina Staniak, Agnieszka Bojko, and Ewa Sikora
6. Autophagy and PTEN in DNA damage-induced senescence
Arishya Sharma and Alexandru Almasan
7. Cellular senescence and tumor promotion: Role of the Unfolded Protein Response
Olivier Pluquet and Corinne Abbadie
8. mTOR as a senescence manipulation target: A forked road
Sarah Saoudaoui, Monique Bernard, Guillaume B. Cardin, Nicolas Malaquin, Apostolos Christopoulos, and Francis Rodier