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Novel Approaches to Colorectal Cancer: Advances in Cancer Research, cartea 151

Franklin G. Berger, C. Richard Boland
en Limba Engleză Hardback – 17 iun 2021
Novel Approaches to Colorectal Cancer, Volume 151 in the Advances in Cancer Research series, is composed of 11 reviews covering state-of-the-art research relating to the etiology, diagnosis, prevention and treatment of colorectal cancer. The book's chapters were written by recognized experts in the field, and include sections on molecular biomarkers in diagnosis and therapy, the interplay of diet, lifestyle, and the microbiome, early-age onset disease, mutational signature analysis, challenges in early detection, immunotherapy, organoid technology, the role of epigenetic alterations, disparities in minority populations, field carcinogenesis, and cancer as an evolutionary process.
Each of these topics provides novel insights and concepts on various aspects of the nature of colorectal cancer, offering new opportunities for the management of a major source of cancer incidence and mortality.


  • Provides information on the timely nature of the included topics, which represent the most current concepts and approaches in cancer research
  • Offers outstanding and original reviews on colorectal cancer research
  • Provides the authority and expertise of the authors, all of whom are highly recognized and conducting state-of-the-art investigations in cancer, with this release focusing on colorectal cancer
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Specificații

ISBN-13: 9780128240786
ISBN-10: 0128240784
Pagini: 484
Dimensiuni: 152 x 229 mm
Greutate: 0.82 kg
Editura: ELSEVIER SCIENCE
Seria Advances in Cancer Research


Public țintă

The volume will be of deep interest to physicians who treat and manage patients diagnosed with colorectal and other cancers, basic scientists, translational researchers, and clinicians. It will be beneficial to educators teaching undergraduate and graduate courses on cancer; corporate and private-sector entities developing new tools and strategies for preventing, detecting, and treating colorectal cancer; and to leaders in public health policy, including governmental, hospital-based, and the insurance industry, as they consider new strategies aimed at reducing the toll of the disease.

Cuprins

1. Early age onset colorectal cancer
Swati G. Patel, Caitlin C. Murphy, Christopher H. Lieu, and Heather Hampel
2. Treatment-induced evolutionary dynamics in nonmetastatic locally advanced rectal adenocarcinoma
Seth I. Felder, Jason B. Fleming, and Robert A. Gatenby
2. Early colorectal cancer detection—Current and evolving challenges in evidence, guidelines, policy, and practices
Robert A. Smith, Stacey Fedewa, and Rebecca Siegel
4. Personalized nutrition for colorectal cancer
Kai Wang and Mingyang Song
5. Immunotherapy in colorectal cancer
Parul Agarwal, Dung T. Le, and Patrick M. Boland
6. Racial and ethnic disparities in colorectal cancer incidence and mortality
John M. Carethers
7. Genomic and epigenomic biomarkers in colorectal cancer: From diagnosis to therapy
Juan Ruiz-Bañobre and Ajay Goel
8. Field carcinogenesis for risk stratification of colorectal cancer
Dionne Rebello, Elliott Rebello, Matthew Custodio, Xixi Xu, Sanil Gandhi, and Hemant K. Roy
9. Modeling colorectal cancers using multidimensional organoids
Ibrahim M. Sayed, Amer Ali Abd El-Hafeez, Priti P. Maity, Soumita Das, and Pradipta Ghosh
10. Unraveling the genomic landscape of colorectal cancer through mutational signatures
Marcos Díaz-Gay and Ludmil B. Alexandrov
11. Epigenetic alterations in the gastrointestinal tract: Current and emerging use for biomarkers of cancer
William M. Grady