Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging
Editat de M. A. Hayaten Limba Engleză Hardback – 15 ian 2017
Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to cellular processes while also inciting researchers to explore their potentially important connections.
- Presents the most advanced information regarding the role of the autophagic system in life and death
- Examines whether autophagy acts fundamentally as a cell survivor or cell death pathway or both
- Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation
- Features recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, including atherosclerosis and CNS tumors, and their development and treatment
- Includes chapters authored by leaders in the field around the globe—the broadest, most expert coverage available
Toate formatele și edițiile | Preț | Express |
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Hardback (10) | 759.71 lei 5-7 săpt. | |
ELSEVIER SCIENCE – 29 sep 2014 | 759.71 lei 5-7 săpt. | |
ELSEVIER SCIENCE – 6 mar 2014 | 805.21 lei 5-7 săpt. | |
ELSEVIER SCIENCE – 11 aug 2014 | 834.96 lei 5-7 săpt. | |
ELSEVIER SCIENCE – 5 ian 2015 | 836.45 lei 5-7 săpt. | |
ELSEVIER SCIENCE – 13 iun 2016 | 836.56 lei 5-7 săpt. | |
ELSEVIER SCIENCE – 29 sep 2013 | 838.07 lei 5-7 săpt. | |
ELSEVIER SCIENCE – 15 ian 2017 | 844.33 lei 5-7 săpt. | |
ELSEVIER SCIENCE – 28 sep 2017 | 853.97 lei 5-7 săpt. | |
ELSEVIER SCIENCE – 24 feb 2016 | 922.52 lei 5-7 săpt. | |
ELSEVIER SCIENCE – 9 iun 2016 | 922.95 lei 5-7 săpt. |
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Specificații
ISBN-13: 9780128054208
ISBN-10: 0128054204
Pagini: 430
Dimensiuni: 191 x 235 x 29 mm
Greutate: 0.95 kg
Editura: ELSEVIER SCIENCE
ISBN-10: 0128054204
Pagini: 430
Dimensiuni: 191 x 235 x 29 mm
Greutate: 0.95 kg
Editura: ELSEVIER SCIENCE
Cuprins
Part I: Molecular Mechanisms 1. Overview of Autophagy 2. Methods for Measuring Autophagosome Flux-Impact and Relevance 3. Loss of Pigment Epithelial Cells Is Prevented by Autophagy 4. Role of Autophagy Inhibition in Regulating Hepatic Lipid Metabolism: Molecular Cross Talk Between Proteasome Activator REG? and SirT1 Signaling 5. Role of Autophagy in Regulating Cyclin A2 Degradation: Live-Cell Imaging 6. Roles of Rab-GAPs in Regulating Autophagy 7. The Role of Histone Deacetylase Inhibition in the Accumulation and Stability of Disease-Related Proteins 8. The Role of Atg9 in Yeast Autophagy
Part II: Role in Disease 9. Methods for Measuring Autophagy Levels in Disease 10. Regulation of the DNA Damage Response by Autophagy 11. Autophagy and Cancer 12. ULK1 Can Suppress or Promote Tumor Growth Under Different Conditions 13. X-Box-Binding Protein 1 Splicing Induces an Autophagic Response in Endothelial Cells: Molecular Mechanisms in ECs and Atherosclerosis 14. Small Molecule–Mediated Simultaneous Induction of Apoptosis and Autophagy 15. Intestinal Autophagy Defends Against Salmonella Infection 16. Autophagy and LC3-Associated Phagocytosis Mediate the Innate Immune Response
Part II: Role in Disease 9. Methods for Measuring Autophagy Levels in Disease 10. Regulation of the DNA Damage Response by Autophagy 11. Autophagy and Cancer 12. ULK1 Can Suppress or Promote Tumor Growth Under Different Conditions 13. X-Box-Binding Protein 1 Splicing Induces an Autophagic Response in Endothelial Cells: Molecular Mechanisms in ECs and Atherosclerosis 14. Small Molecule–Mediated Simultaneous Induction of Apoptosis and Autophagy 15. Intestinal Autophagy Defends Against Salmonella Infection 16. Autophagy and LC3-Associated Phagocytosis Mediate the Innate Immune Response
Recenzii
"Editor Hayat presents this first volume of a four-volume series on autophagic processes, with an introduction to the series giving a broad overview of autophagy in the healthy state and a selection of disease states. This volume focuses primarily on the role of autophagy in chronic diseases and cancer." --ProtoView.com, February 2014