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Bioactive Natural Products for the Management of Cancer: from Bench to Bedside

Editat de Anil K. Sharma
en Limba Engleză Hardback – 5 aug 2019
This book illustrates the importance of the Natural Biometabolites, which offer a rich reservoir of candidate compounds for drug discovery in the battle against cancer. Recent research and development efforts concerning anti-cancer drugs derived from natural products have led to the identification of numerous candidate molecules that inhibit cancer cell proliferation and metastasis using a variety of mechanisms.
Given its scope, the book offers a valuable resource for cancer biologists and general oncologists alike, while also benefitting research professionals in Science, Nursing, Medicine, Biochemistry, Genetics and Bioscience who wish to understand the fundamentals of prognosis and prediction in tumorigenesis. Moreover, the book provides an essential platform for understanding drug resistance mechanisms and combatting the growing menace of multidrug resistance.
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Specificații

ISBN-13: 9789811376061
ISBN-10: 9811376069
Pagini: 280
Ilustrații: IX, 218 p. 115 illus., 28 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.5 kg
Ediția:1st ed. 2019
Editura: Springer Nature Singapore
Colecția Springer
Locul publicării:Singapore, Singapore

Cuprins

- Anticancer Alkaloids: Molecular Mechanisms and Clinical Manifestations. - Emerging Alkaloids Against Cancer: A Peep into Factors, Regulation, and Molecular Mechanisms. - Mechanistic Insight into Cancer Aetiology and Therapeutic Management by Natural Metabolites. - Flavones: Flavonoids Having Chemico-Biological Properties with a Preview into Anticancer Action Mechanism. - Cancer Chemoprevention by Dietary Polyphenols, Flavonoids, Terpenoids, and Saponins. - Immunogenic Potential of Natural Products. - Immunomodulatory and Therapeutic Potential of Marine Flora Products in the Treatment of Cancer. - Ligand-Based Designing of Natural Products. - Drug Resistance in Cancer and Role of Nanomedicine-Based Natural Products.

Notă biografică

Dr. Anil K Sharma is presently at M.M. (DU), Department of Biotechnology, Mullana, Ambala (India), where he has been a Professor and Head of the Department since April 2012. Previously, he worked as a Senior Research Scientist in Health Sciences (UIC Chicago, USA; 2008-2010), Postdoctoral Research Fellow in Molecular Biology (Micro and Immunology Department, UIC Chicago, IL, USA; 2003-2008), and Senior Research Scientist at Ranbaxy (R&D, Gurgaon, Haryana, India; 2001-2003). He has authored more than 95 publications in peer-reviewed journals and received many prestigious awards and accolades including an Eminent Scientist Award for Molecular & Microbial Science (2017 & 2018), National Achiever Award (2016), and Bharat Excellence Award (2013). In addition to editing five books, he has been the Editor-in-Chief of two journals, and lead guest editor, editorial board member or reviewer of over 30 more. 

Textul de pe ultima copertă

This book illustrates the importance of the Natural Biometabolites, which offer a rich reservoir of candidate compounds for drug discovery in the battle against cancer. Recent research and development efforts concerning anti-cancer drugs derived from natural products have led to the identification of numerous candidate molecules that inhibit cancer cell proliferation and metastasis using a variety of mechanisms.
Given its scope, the book offers a valuable resource for cancer biologists and general oncologists alike, while also benefitting research professionals in Science, Nursing, Medicine, Biochemistry, Genetics and Bioscience who wish to understand the fundamentals of prognosis and prediction in tumorigenesis. Moreover, the book provides an essential platform for understanding drug resistance mechanisms and combatting the growing menace of multidrug resistance.

Caracteristici

The book comprehensively provide the recent updates on Natural metabolites and their therapeutics use against Cancer It summarize the distinctive pathways and mechanistic insight into the mode of action of Natural metabolites It highlights the utilization of nanoparticle-augmented Adjuvant therapy to enhance Pharmacodynamic and Pharmacokinetic Potency of Natural metabolites It elucidates designing of Ligand-based Drug from the Natural metabolites to enhance their active potential and counter adverse side effects