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Bioinformatics and Human Genomics Research

Editat de Diego A. Forero
en Limba Engleză Paperback – 29 ian 2024
Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide
expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.
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Specificații

ISBN-13: 9781032028934
ISBN-10: 1032028939
Pagini: 374
Ilustrații: 49
Dimensiuni: 178 x 254 mm
Greutate: 1 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press

Notă biografică

Diego A. Forero, MD, PhD is Professor and Research Leader at the School of Health and Sport Sciences, Fundación Universitaria del Área Andina (Bogotá, Colombia). He is a Medical Doctor (Universidad Nacional de Colombia, Colombia, 2003) and PhD in Biomedical Sciences (University of Antwerp, Belgium, 2009) and has a recognized track record in research on genetics and genomics. He has authored 107 international scientific publications, has a cumulative impact factor of 373,750 and a h-index of 27. He is Senior Editorial Member of BMC Research Notes, has been peer reviewer for 91 international scientific publications and for 28 academic and scientific institutions.

Cuprins

1. Bioinformatics and Human Genomics Research: An Introduction   2. Bioinformatics of Genome Annotation  3. Protein Function Prediction: Human Sequences and Structures  4. Bioinformatics and Genomic Data Mining  5. Bioinformatics of Genome-wide Expression Studies  6. Whole-genome Sequencing: From Samples to Variants and Beyond  7. Bioinformatics for Whole Exome Studies  8. Bioinformatics of Variant Effect Prediction  9. Bioinformatics of Genome-wide DNA Methylation Studies  10. Bioinformatics of Transcription Factor Binding Prediction  11. Bioinformatics of Prediction of Secondary Structures of Non-coding RNAs  12. Bioinformatics of microRNA Target Prediction  13. Bioinformatics and Network Analysis of Biological Data  14. Bioinformatics of Functional Categories Enrichment  15. Bioinformatics of Meta-analyses of Genomic Data  16. Clinical Data Integration with Cancer Genomics: Insights Into Computational and Quantitative Methods  17. Bioinformatics of Correction of Multiple Testing: An Introduction for Life Scientists (in Bioinformatics and Human Genomics Research) 

Descriere

The book Bioinformatics and Human Genomics Research provides up to date and comprehensive information about multiple approaches of bioinformatic tools in research in human genomics. Experts, from around the worlds of the applications in bioinformatics and human genomics have contributed chapters in the book.