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Biological Calcification: Normal and Pathological Processes in the Early Stages

Autor Ermanno Bonucci
en Limba Engleză Hardback – 11 dec 2006
For the first time, this book offers a critical review of the calcification process of the organic and inorganic phases of mineralized tissues focusing on the earliest phases. It includes a methodological chapter which provides the necessary practical information for making appropriate choices. The book is set to become an important reference source for the shelves of bone densitometry labs across the world.
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Specificații

ISBN-13: 9783540360124
ISBN-10: 3540360123
Pagini: 616
Ilustrații: XXII, 592 p. 48 illus.
Dimensiuni: 155 x 235 x 38 mm
Greutate: 1.1 kg
Ediția:2007
Editura: Springer Berlin, Heidelberg
Colecția Springer
Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Professional/practitioner

Descriere

This book follows a precursor volume devoted to biological calci?cation, - sued by the CRC Press, Boca Raton (Florida) in 1992. Several basic aspects of the calci?cation process were analyzed in it by outstanding authors who had unquestioned competence in their respective research areas. Its main aim was that of giving readers access to a series of papers which, even though they discussed divergent aspects of biological calci?cations drawn from the study of systems as different as vertebrate skeletons and mollusks, in vitro cultures and unicellular organisms, ectopic calci?cation and urinary stones, provided elements permitting a coherent approach to a comprehensive view of the calci?cation process in biological tissues. Now, almost 15 years after the publication of that book, a great variety of new data from a wide spectrum of biological organisms and systems has enriched our knowledge of the normal and pathological mechanisms which can lead to calci?cation. Even so, this whole process is still problematic: the new knowledge, concepts and ideas have often suggested that a de?nitive solution was close at hand, but the local mechanism through which the inorganic substance is laid down in organic matrices continues to be an elusive, largely enigmatic topic.

Cuprins

Historical Notes.- Methodology.- The Nature and Composition of the Inorganic Phase.- The Shape of Inorganic Particles.- The Size of Inorganic Particles.- Calcifying Matrices: Bone and Tendons.- Calcifying Matrices: Dentin and Cementum.- Calcifying Matrices: Cartilage.- Calcifying Matrices: Enamel.- Calcifying Matrices: Lower Vertebrates.- Calcifying Matrices: Invertebrates.- Calcifying Matrices: Non-skeletal Structures.- Calcifying Matrices: Pathological Calcifications.- Calcifying Matrices: Acquired or Experimental Diseases; Heritable Disorders; Genetically Modified Animals.- The Organic-inorganic Relationships in Calcifying Matrices.- Main Suggested Calcification Mechanisms: Cells.- Main Suggested Calcification Mechanisms: Extracellular Matrix.- Conclusions.

Caracteristici

Author has been involved in studies of biological calcification for over forty years
Plain, concise, and easy to read
Developing quite slowly; thus the book might become a reference source for many years to come
Set to become an important reference source for the shelves of bone densitometry labs across the world
Includes supplementary material: sn.pub/extras