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Biology of Serpins de James Whisstock

Biology of Serpins: Methods in Enzymology, cartea 499

Editat de James Whisstock, Phillip Bird
en Limba Engleză Hardback – 24 aug 2011
Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. This volume of Methods in Ezymology is split into 2 parts and comprehensively covers the subject.
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Specificații

ISBN-13: 9780123864710
ISBN-10: 0123864712
Pagini: 456
Dimensiuni: 152 x 229 x 30 mm
Editura: ELSEVIER SCIENCE
Seria Methods in Enzymology

Public țintă

Researchers and students in cell, molecular and developmental biology

Cuprins

  1. Analysis of Serpin Secretion, Misfolding and Surveilance in the Endoplasmic Reticulum Shujuan Pan, Michael J. Iannotti and Richard N. Sifers
  2. Serpin-Enzyme Receptors: Ldl Receptor Related Protein 1 Dudley K. Strickland, Selen Catania Muratoglu and Toni M. Antalis
  3. The Role of Autophagy in Alpha-1-Antitrypsin Deficiency Tunda Hidvegi, Amitava Mukherjee, Michael Ewing, Carolyn Kemp and David H. Perlmutter
  4. Serpins and the Complement System László Beinrohr, Thomas A. Murray-Rust, Leanne Dyksterhuis, Péter Závodszky, Péter Gál, Robert N. Pike and Lakshmi C. Wijeyewickrema
  5. Use of Mouse Models to Study Plasminogen Activator Inhibitor-1 Paul J. Declerck, Ann Gils and Bart De Taeye
  6. Plasminogen Activator Inhibitor Type 2: Still An Enigmatic Serpin But A Model For Gene Regulation Robert L. Medcalf
  7. The Serpinb1 Knock-Out Mouse: A Model For Studying Neutrophil Protease Regulation in Homeostasis and Inflammation Charaf Benarafa
  8. Investigating Maspin in Breast Cancer Progression Using Mouse Models Michael P. Endsley and Ming Zhang
  9. Hsp47as A Collagen-Specific Molecular Chaperone Yoshihito Ishida and Kazuhiro Nagata
  10. Assays for the Antiangiogenic and Neurotrophic Serpin Pigment Epithelium-Derived Factor S. Patricia Becerra, Susan E. Crawford and Preeti Subramanian
  11. The Drosophila Serpins: Multiple Functions in Immunity and Morphogenesis Jean Marc Reichhart, David Gubb and Vincent Leclerc
  12. Modelling Serpin Conformational Diseases in Drosophila Melanogaster Thomas R. Jahn, Elke Malzer, John Roote, Anastasia Vishnivetskaya, Sara Imarisio, Maria Giannakou, Karin Panser, Stefan Marciniak, Damian C. Crowther
  13. Using Caenorhabditis Elegans to Study Serpinopathies Olivia S. Long, Sager J. Gosai, Joon Hyeok Kwak, Dale E. King, David H. Perlmutter, Gary A. Silverman and Stephen C. Pak
  14. Using c. Elegans to Identify the Protease Targets of Serpins In Vivo. Sangeeta R. Bhatia, Mark T. Miedel, Cavita K. Chotoo, Nathan J. Graf, Brian L. Hood, Thomas P. Conrads, Gary A. Silverman and Cliff J. Luke
  15. Viral Serpin Therapeutics: From Concept to Clinic Hao Chen, MD, PhD, Donghang Zheng, MD, PhD, Jennifer Davids, BA, Mee Yong Bartee, PhD, Erbin Dai, MD, Liying Liu, MD, Lyubomir Petrov, MD, PhD, Colin Macaulay, PhD, Robert Thoburn, MD, Eric Sobel, MD, PhD, Richard Moyer, PhD, Grant McFadden, PhD, Alexandra Lucas, MD, FRCP(C)
  16. Human Scca Serpins Inhibit Staphylococcal Cysteine Proteases by Forming Classic "Serpin-Like" Covalent Complexes Tomasz Kantyka and Jan Potempa
  17. Plants and the Study of Serpin Biology
Thomas H. Roberts, Joon-Woo Ahn, Nardy Lampl and Robert Fluhr