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Biology of the NMDA Receptor de Antonius M. VanDongen

Biology of the NMDA Receptor

Editat de Antonius M. VanDongen
en Limba Engleză Paperback – 10 oct 2019
The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written by one of the world’s leading authorities on NMDA receptors, Biology of the NMDA Receptor brings together virtually all the players in this important field.
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Specificații

ISBN-13: 9780367386528
ISBN-10: 0367386526
Pagini: 350
Dimensiuni: 156 x 234 x 22 mm
Greutate: 0.68 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press

Public țintă

Academic, Professional Practice & Development, and Professional Reference

Cuprins

Introduction. Molecular Genetics of the NMDA Receptor. NMDA Receptors: Learning and Memory. The Role of NMDA Receptors in Organizing Brain Development. NMDA Receptors and Developmental Critical Periods. NMDA Receptors and Spine Morphogenesis. NMDA Receptors and Synaptic Plasticity. NMDA Receptor Signaling to the Nucleus. Trafficking and Targeting of NMDA Receptors. Regulation of NMDA Receptor Function by Phosphorylation. Allosteric Modulation of the NMDA Receptor. Pharmacology of the NMDA Receptor. Activation of the NMDA Receptor. Structural Biology of the NMDA Receptor.

Descriere

The NMDA receptor, a subclass of the ionotropic glutamate receptor family, plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. Biology of the NMDA Receptor describes all importance aspects of NMDA receptor biology. The text highlights exciting new discoveries that have been made over the past decade. It provides a comprehensive review of various molecular genetics studies that illustrate the importance of this class of receptors; in addition, the book presents a discussion of recent crystallographic x-ray structures of its ligand binding domains.