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Biotechnologies for Gene Therapy: RNA, CRISPR, Nanobots, and Preclinical Applications

Editat de Yang H. Yun, Kristine E. Yoder
en Limba Engleză Paperback – 4 iun 2023
The purpose of this book is to highlight some of latest developments and applications of CRISPR, RNA, and DNA to treat diseases ranging from cancers to cardiovascular and degenerative disorders. It also features innovations of the delivery methods for nucleic acids ranging from nanodevices made from DNA and pseudo amino acids to viral vectors. This is an ideal book for academics, clinicians, and students interested in gene therapy.
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Specificații

ISBN-13: 9783030933357
ISBN-10: 3030933350
Ilustrații: IX, 203 p. 26 illus., 23 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.34 kg
Ediția:1st ed. 2022
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

1. Therapeutic potential of microRNAs and their nanoparticle-based delivery in the treatment of liver fibrosis
2. MicroRNA as a versatile regulator of Wnt signaling pathway in colorectal cancer
3. Small Activating RNA Therapy for Angiogenesis
4. Muscular dystrophy therapy using viral vector-based CRISPR/Cas
5. CRISPR-Cas based gene therapy to target viral infections
6. CRISPR targeting the integrated HTLV-1 virus
7. Retroviral vectors for gene therapy of monogenic diseases
8. DNA Origami Nanodevices for Therapeutic Delivery Applications


Notă biografică

Dr. Yang Yun is an Associate Professor in the Biomedical Engineering Department at the University of Akron. His research interested include biomaterials, cancer therapy, drug and gene delivery, electrospinning, nanotechnology, tissue engineering, and the treatment of infectious diseases.

Dr. Kristine Yoder is  an Associate Professor in the department of Cancer Biology and Genetics at Ohio State University.

Textul de pe ultima copertă

The purpose of this book is to highlight some of latest developments and applications of CRISPR, RNA, and DNA to treat diseases ranging from cancers to cardiovascular and degenerative disorders. It also features innovations of the delivery methods for nucleic acids ranging from nanodevices made from DNA and pseudo amino acids to viral vectors. This is an ideal book for academics, clinicians, and students interested in gene therapy.

Caracteristici

Addresses the delivery microRNA and CRISPR for a variety of diseases, including cancer and cardiovascular disease
Illustrates the delivery methods and techniques for preclinical applications of miroRNA and CRISPR gene therapy
Identifies biotechnologies for gene therapy that have the potential for developing into new clinical therapies