Boundaries between Promotion and Progression during Carcinogenesis: Basic Life Sciences, cartea 57
Editat de Oscar Sudilovsky, Henry C. Pitot, L.A. Liottaen Limba Engleză Paperback – 25 noi 2012
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Specificații
ISBN-13: 9781468459968
ISBN-10: 1468459961
Pagini: 388
Ilustrații: 384 p.
Dimensiuni: 178 x 254 x 20 mm
Greutate: 0.67 kg
Ediția:1991
Editura: Springer Us
Colecția Springer
Seria Basic Life Sciences
Locul publicării:New York, NY, United States
ISBN-10: 1468459961
Pagini: 388
Ilustrații: 384 p.
Dimensiuni: 178 x 254 x 20 mm
Greutate: 0.67 kg
Ediția:1991
Editura: Springer Us
Colecția Springer
Seria Basic Life Sciences
Locul publicării:New York, NY, United States
Public țintă
ResearchCuprins
Introduction: Is there a Boundary Between Promotion and Progression.- Session I: The Boundaries between Promotion and Progression in Different Tissues.- Characterization of the Stage of Progression in Hepatocarcinogenesis in the Rat.- Critical Events in Skin Tumor Promotion and Progression.- Malignant Conversion, the First Stage in Progression, is distinct from Phorbol Ester Promotion in Mouse Skin.- Boundaries in Mammary Carcinogenesis.- Discussion of Session.- Session II: Development and Boundaries between Promotion and Progression.- Progression in Teratocarcinomas.- Developmental Potential of Murine Pluripotent Stem Cells.- Summary by Moderator:.- Colloquium: Transgenic Mice and the Boundaries between Promotion and Progression.- Tumor Progression in Transgenic Mice Containing the Bovine Papillomavirus Genome.- SV40 T Antigen Transgenic Mice: Cytotoxic T Lymphocytes as a Selective Force in Tumor Progression*.- Session III: Oncogenes, Suppressor Genes and the Boundaries between Promotion and Progression.- Differential Gene Expression During Tumor Promotion and Progression in the Mouse Skin Model.- Oncogenes and Breast Cancer Progression.- Gene Amplification During Stages of Carcinogenesis.- Recessive Mutations in Cancer Predisposition and Progression.- Role of Tumor Suppressor Genes in a Multistep Model of Carcinogenesis.- Cancer Genes by Non-Homologous Recombination.- Discussion of Session.- Session IV: Genetic Instability and the Boundaries between Promotion and Progression.- Genetic Instability and Tumor Development.- Unknown Primary Tumors: An Example of Accelerated (Type 2) Tumor Progression.- Discussion by Moderator.- Colloquium: At Which Point in Time Does Genetic Instability Occur in the Natural History of Cancer?.- Tumor Heterogeneity and Intrinsically Chemoresistant Subpopulations in Freshly Resected Human Malignant Gliomas.- Genetic Instability Occurs Sooner Than Expected: Promotion, Progression and Clonality During Hepatocarcinogenesis in the Rat.- Clonal Analysis of Neoplastic Transformation in Cultured Diploid Rat Liver Epithelial Cells.- Epigenetic Features of Spontaneous Transformation in the NIH 3T3 Line of Mouse Cells.- Session V: The Boundaries between Promotion and Progression in Humans.- The Human Melanocyte System as a Model for Studies on Tumor Progression.- Early and Late Events in the Development of Human Breast Cancer.- Malignant Progression in Harvey Ras Transformed Normal Human Bronchial Epithelial Cells.- Identification and Characterization of Differentially Expressed Genes in Tumor Metastasis: The nm23 Gene.