The anticipation of biological and clinical utility of biomarkers has attracted important interest. Significant molecular biomarkers for cancers have applications for establishing disease predisposition, early detection, cancer staging, therapy selection, identifying whether or not a cancer is metastatic, therapy monitoring, assessing prognosis, and advances in the adjuvant setting. This book presents current research data from across the globe in the study of cancer biomarkers, including oral cancer biomarkers through a cell cycle perspective; molecular markers of infectious agents to detect cancer; protein isoforms; bioinformatics analysis of gene networks involved in genomic stability and cancer; comet assay in human biomonitoring; metabolomics; and immunoelectrophoresis to detect immunoglobins of myeloma patients.