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Chemistry of Antibiotics and Related Drugs

Autor Mrinal K. Bhattacharjee
en Limba Engleză Paperback – 25 aug 2023
This textbook builds on the success of the earlier edition, offering alternative strategies for discovering new antibiotics. It discusses how the various types of antibiotics and related drugs work to cure infections. Then it delves into the very serious matter of how bacteria are becoming resistant to these antibiotics. It also covers the global action plan on antimicrobial resistance from the World Health Organization and discusses several Antibiotic Stewardship Programs adopted by agencies at local levels.
Appropriate for a one-semester course at either the graduate or advanced undergraduate level, the book is self-contained and written in accessible language. It includes all necessary background biochemistry material and a discussion of the latest developments in the field of antibiotics. Original research works are frequently cited and experimental procedures and interpretation of results are emphasized.
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Specificații

ISBN-13: 9783031075841
ISBN-10: 3031075846
Pagini: 268
Ilustrații: XIII, 268 p. 109 illus., 36 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.4 kg
Ediția:2nd ed. 2022
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

Chapter 1: Introduction.- Chapter 2: Development of resistance to antibiotics.- Chapter 3: Antibiotics that inhibit cell wall synthesis.- Chapter 4: Antimetabolites: Antibiotics that inhibit nucleotide synthesis.- Chapter 5: Antibiotics that inhibit nucleic acid synthesis.- Chapter 6: Antibiotics that inhibit protein synthesis.- Chapter 7: Antibiotics that affect the membrane and other structural targets.- Chapter 8: Antifungals, Antimalarials and Antivirals.- Chapter 9: Alternative Approaches for Antibiotic Discovery.- Chapter 10: Global Action Plan and Antibiotic Stewardship.

Notă biografică

Mrinal Bhattacharjee did his Ph.D. from The Ohio State University and currently works as an Associate Professor at Long Island University where he teaches Biochemistry, Organic Chemistry and General Chemistry classes. His research interests include molecular biology of oral bacteria and the discovery and study of new antibiotics, especially from natural sources.

Textul de pe ultima copertă

This textbook builds on the success of the earlier edition, offering alternative strategies for discovering new antibiotics. It discusses how the various types of antibiotics and related drugs work to cure infections. Then it delves into the very serious matter of how bacteria are becoming resistant to these antibiotics. It also covers the global action plan on antimicrobial resistance from the World Health Organization and discusses several Antibiotic Stewardship Programs adopted by agencies at local levels.
Appropriate for a one-semester course at either the graduate or advanced undergraduate level, the book is self-contained and written in accessible language. It includes all necessary background biochemistry material and a discussion of the latest developments in the field of antibiotics. Original research works are frequently cited and experimental procedures and interpretation of results are emphasized.


Caracteristici

Expands on earlier edition with new strategies for antibiotic discovery Outlines the WHO global action plan on antimicrobial resistance Suitable for a one-semester course on Antibiotics and Development of Resistance to Antibiotics

Recenzii

“In the Chemistry of Antibiotics and Related Drugs, Bhattacharjee (chemistry and biochemistry, Long Island Univ.) writes about the many different classes of compounds approved over the last century that still are, or have been, used to treat infectious diseases. The book is organized around the targets of these compounds. … this book is heavily referenced and will be valuable to practicing researchers and advanced students. Summing Up: Recommended. Upper-division undergraduates and above; faculty and professionals.” (P. W. Baures, Choice, Vol. 54 (9), May, 2017)