Cholera Toxins
Autor Keya Chaudhuri, S. N. Chatterjeeen Limba Engleză Paperback – 19 oct 2010
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Springer Berlin, Heidelberg – 19 oct 2010 | 985.08 lei 39-44 zile | |
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Specificații
ISBN-13: 9783642100116
ISBN-10: 3642100112
Pagini: 336
Ilustrații: XIV, 321 p.
Dimensiuni: 155 x 235 x 18 mm
Ediția:Softcover reprint of hardcover 1st ed. 2009
Editura: Springer Berlin, Heidelberg
Colecția Springer
Locul publicării:Berlin, Heidelberg, Germany
ISBN-10: 3642100112
Pagini: 336
Ilustrații: XIV, 321 p.
Dimensiuni: 155 x 235 x 18 mm
Ediția:Softcover reprint of hardcover 1st ed. 2009
Editura: Springer Berlin, Heidelberg
Colecția Springer
Locul publicării:Berlin, Heidelberg, Germany
Public țintă
ResearchCuprins
An Introduction to Cholera.- Bacterial Toxins: A Brief Overview.- Vibrio cholerae, the Causative Organism.- Endotoxin of Vibrio cholerae: Physical and Chemical Characterization.- Endotoxin of Vibrio cholerae: Genetics of Biosynthesis.- Endotoxin of Vibrio cholerae: Biological Functions.- Cholera Toxin (CT): Structure.- Cholera Toxin (CT): Organization and Function of the Relevant Genetic Elements.- Cholera Toxin (CT): Regulation of the Relevant Virulence Genes.- Cholera Toxin (CT): Secretion by the Vibrios.- Cholera Toxin (CT): Entry and Retrograde Trafficking into the Epithelial Cell.- Cholera Toxin (CT): Immune Response of the Host and Vaccine Production.- Other Toxins of Vibrio cholerae.- Concluding Notes.
Notă biografică
Dr. Keya Chaudhuri (b. 1952) obtained her PhD degree from Jadavpur University in 1983 and is presently working as Senior Scientist & Deputy Director at the Molecular & Human Genetics Division of the Indian Institute of Chemical Biology, Kolkata, India. Her research focuses on Vibrio cholerae infection, mainly on the cellular and molecular mechanisms of the disease-process, with special emphasis on the identification of bacterial gene products that become apparent during the infection as well as their role in V. cholerae pathogenesis and the elucidation of host response at the molecular level. Besides Vibrio cholerae, her research interest includes bioinformatics and cancer biology.
Professor S. N. Chatterjee (b. 1932) received his PhD degree from the University of Calcutta in 1958. He worked for several years as Associate Professor & Head of the Biophysics Department at the Calcutta School of Tropical Medicine and then as Senior Professor & Chairman (1977–1992) of the Biophysics Division and Director (1990-1991) of the Saha Institute of Nuclear Physics in Kolkata. Subsequently he continued to work at the SINP as Senior Scientist, an emeritus-ship awarded by the Indian National Science Academy, New Delhi. Besides Vibrio cholerae and cholera bacteriophages, his research interests include the electron microscopy of biomolecules, free radicals biology involving ultrasound and UVA, and the molecular toxicology of nitrofurans. He is a fellow of several academies and recipient of many awards.
Professor S. N. Chatterjee (b. 1932) received his PhD degree from the University of Calcutta in 1958. He worked for several years as Associate Professor & Head of the Biophysics Department at the Calcutta School of Tropical Medicine and then as Senior Professor & Chairman (1977–1992) of the Biophysics Division and Director (1990-1991) of the Saha Institute of Nuclear Physics in Kolkata. Subsequently he continued to work at the SINP as Senior Scientist, an emeritus-ship awarded by the Indian National Science Academy, New Delhi. Besides Vibrio cholerae and cholera bacteriophages, his research interests include the electron microscopy of biomolecules, free radicals biology involving ultrasound and UVA, and the molecular toxicology of nitrofurans. He is a fellow of several academies and recipient of many awards.
Textul de pe ultima copertă
Vibrio cholerae, the causative organism of the disease Cholera, colonizes the small intestine and produces several different toxins among which the enterotoxin, or more widely known as cholera toxin (CT), happens to be the major virulence determinant that is responsible for the diarrheal syndrome. This book provides for the first time comprehensive and up-to-date information about all the toxins of Vibrio cholerae, their physical and chemical structures, their biosynthesis and its genetic regulation, their physiology, the molecular biology of their interactions with the host as well as their role in the development of an appropriate and effective cholera vaccine. It also offers relevant and necessary background information on the basic biology of the Vibrio cholerae cell and cholera bacteriophages.
Caracteristici
Focuses on all toxins produced by the "Vibrio cholerae" cell and presents the current state of knowledge of the molecular biology of these toxins Includes supplementary material: sn.pub/extras