Chondrogenesis of the Somitic Mesoderm: Advances in Anatomy, Embryology and Cell Biology, cartea 53/4

1. Development and Division of the Somite.- 1.1. Migration of Pre-somitic Mesoderm.- 1.2. Segmentation of the Mesoderm into Somites.- 1.3. Subdivision of the Somites.- 1.4. Spinal Ganglia.- 2. Self Differentiation or Induction.- 2.1. 1925–1940: Grafts to the Avian Chorioallantoic Membrane.- 2.2. 1940’s–1950’s: In vivo Transplantation and Extirpation.- 2.3. 1950’s Onwards”: In vitro Chondrogenesis.- 3. The Inductive Tissues.- 3.1. Integrity of the Inducer and Vertebral Morphogenesis.- 3.2. When Do the Inducers Lose Their Inductive Ability?.- 3.3. Ability of Dermomyotome to Chondrify.- 3.4. The Search for a Pure Inducer.- 4. Ectopic Inducers.- 4.1. Can Ectoderm Act Inductively on Somites?.- 4.2. Other Ectopic (heterologous) Inducers.- 5. Synthesis of Glycosaminoglycans and Onset of Cartilage Differentiation.- 6. Production of Extracellular Matrix by Notochord and by Spinal Cord.- 6.1. Glycosaminoglycans.- 6.2. Collagen.- 7. Function of Extracellular Matrix Produced by Notochord and Spinal Cord.- 8. Discussion and Conclusions.- 9. Summary.- References.- Author Index.