The disease in which cancer cells develop in the glandular organ situated behind the stomach, known as pancreas, is referred to as Pancreatic Cancer. The treatment, clinical processes and risk factors related to the severe disease of pancreatic cancer have been discussed in this book. It elucidates the biomarkers, genetic risk factors and systems biology of the disease for its better comprehension. Since pancreatic cancer is often linked with lack of early detection or prognosis markers, this book elucidates genetic makers and stem cells to recognize this disease in its initial stages. Furthermore, it describes the efficiency and adequacy of monotherapy and combination therapy in fighting this acute disease. Due to rise of immunotherapy as an efficient approach for stemming the progression of pancreatic cancer, this profound book encompasses several aspects of immunotherapy including adaptive, passive, innate, active and bacterial approaches. Management of anesthesia during surgery and postoperative pain has also been elaborated. An updated in-depth description on the role of endoscopy and fine needle guided biopsies in diagnosing and examining the progression of the disease has also been provided in this book.