Color Atlas of Nerve Biopsy Pathology
Editat de Shin J. Ohen Limba Engleză Hardback – 31 iul 2001
Providing all the practical information you need from A to Z, Color Atlas of Nerve Biopsy Pathology describes how to:
- perform a nerve biopsy
- handle specimens
- process the nerve by frozen sections, by paraffin sections, and by semi-thin sections
The book delineates the general pathological features of peripheral nerve disorders and the diagnostic capability and limitations of the nerve biopsy. It details the typical pathological features of each disease by presenting color photographs and example cases that provide a brief clinical history and pertinent electrophysiological and other laboratory data. The exhaustively illustrated color format provides you with immediate information in reaching a definitive diagnosis.
Unlike other books on this subject, this one contains frozen section materials, case histories, teased nerve illustrations, and newly described neuropathies. The author brings twenty-five years of experience in the lab and teaching to the development of this atlas. In the lab or in the classroom, on the front lines of tissue diagnosis, Color Atlas of Nerve Biopsy Pathology provides you with the information you need clearly, concisely, and conveniently.
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Specificații
ISBN-13: 9780849316760
ISBN-10: 0849316766
Pagini: 298
Ilustrații: 255 b/w images, 20 tables and 257 halftones
Dimensiuni: 177 x 267 x 22 mm
Greutate: 0.76 kg
Ediția:New.
Editura: CRC Press
ISBN-10: 0849316766
Pagini: 298
Ilustrații: 255 b/w images, 20 tables and 257 halftones
Dimensiuni: 177 x 267 x 22 mm
Greutate: 0.76 kg
Ediția:New.
Editura: CRC Press
Public țintă
Graduate students and residents in neuropathology, neurology, and pathology; neurologists, neuropathologists, general pathologists forensic pathologists,orthopedics, and neurophysiologists; medical school libraries, and health science bookstoresContact Editor: Carol Hollander
Cuprins
GENERAL CONCEPTS OF PERIPHERAL NEUROPATHY
Classification of Peripheral Neuropathy
Basic Pathological Mechanism
Etiologies of Peripheral Neuropathy
Types of Neuropathies
Symptoms and Signs
Diagnostic Investigations
Nerve Conduction Studies and Needle Electromyography
Laboratory Studies
THE NERVE BIOPSY
Indication for the Nerve Biopsy
Types of Nerve Biopsy
Sural Nerve Biopsy
Sequelae of Nerve Biopsy
Biopsy of Other Nerves
HISTOLOGICAL PROCESSING AND STAINING OF THE BIOPSIED NERVE
Treatment of the Biopsied Nerve
Immediate Care of the Biopsied Nerve
Processing of the Nerve
Paraffin Section Stainings
Frozen Section Stainings
Processing of the Nerve for Semithin and Electron Microscopy Sections
Semithin (0.5 - 1mm) Section Stainings
Nerve Fiber Teasing
Electron Microscope Study
NORMAL NERVE: HISTOLOGY
Age-Related Changes in the Sural Nerve Biopsy
SPECIFIC DIAGNOSTIC PATHOLOGICAL FEATURES OF NERVE BIOPSY
Vasculitis
Amyloid Deposits
Metachromatic Granules
Polyglucosan Body
Onion-Bulb Formation
Inflammatory Cells and Segmental Demyelination
INFLAMMATORY CELLS AND AXONAL DEGENERATION
Noncaseating Granuloma
Necrotizing (Caseating) Granuloma
Giant Axons
Tomacula
Occlusion of Vasa Nervorum
Malignant Cells
IgM Deposits
Segmental Demyelination
Axonal Degeneration
VASCULITIC NEUROPATHY
Vulnerability of the Peripheral Nerve to Vasculitic neuropathy
Clinical, Electromyographic, and Laboratory Features
Diagnostic Sensitivity of Nerve and Muscle Biopsies
Pathology of Vasculitic Neuropathy
Pathogenesis of Vasculitic Neuropathy
Systemic Necrotizing Vasculitides
Vasculitis Associated with Connective Tissue Diseases
Nonsystemic Vasculitic Neuropathy
Vasculitis in Other Diseases
Cases with Vasculitic Neuropathy
INFLAMMATORY DEMYELINATING NEUROPATHY
Pathogenesis of Inflammatory Demyelinating Neuropathies
Guillain-Barré Syndrome (Acute inflammatory Demyelinating Polyneuropathy; AIDP)
Variants of GBS
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Multifocal Motor Neuropathy (MMN)
Multifocal Motor Sensory Demyelinating Neuropathy (MMSDN)
Chronic Sensory Demyelinating Neuropathy (CSDN)
Cases of Inflammatory Demyelinating Neuropathy
IMMUNE-MEDIATED NEUROPATHIES
GM1 Antibody-Positive Neuropathy
Anti-MAG Associated Neuropathy
Neuropathy Associated with Anti-Hu (ANNA 1) Antibody
Neuropathy with Monoclonal Gammopathy
Cases of Immune-Mediated Neuropathy
NEUROPATHIES WITH ABNORMAL DEPOSITS
Amyloid Neuropathy
Metachromatic Leukodystrophy (Sulfatide Lipidosis; Arylsulfatidase Deficiency)
Polyglucosan Body Neuropathy
Fabry's Disease (Alpha-Galactosidase-A Deficiency)
Adrenomyeloneuropathy (AMN)
Cases of Neuropathy with Abnormal Deposit
HEREDITARY NEUROPATHIES
Hereditary Motor and Sensory Neuropathies (HMSN)
Hereditary Sensory Neuropathy
Hereditary Neuropathy to Pressure Palsy (HNPP)
Giant Axonal Neuropathy (GAN)
Friedreich's Ataxia
METABOLIC AND SYSTEMIC NEUROPATHIES
Sarcoid Neuropathy
Sensory Perineuritis
Leprosy
Lymphomatous Neuropathy
Diabetic Neuropathy
Uremic Neuropathy
Alcoholic Neuropathy
Hypothyroid Neuropathy
Vitamin B12 Deficiency Neuropathy
Pyridoxine-Induced Sensory Neuropathy
Polyradiculoneuropathy in Lyme Disease
AIDS Neuropathy
TOXIC NEUROPATHIES
Metal Neuropathies
Drug-Induced Neuropathy
Neuropathy Due to Biological Toxins and Vaccines
Toxic Neuropathy Due to Industrial and Environmental Agents
Epidemic Toxic Inflammatory Neuropathies
Cases of Toxic Neuropathies
INTERPRETATION OF NERVE BIOPSY
INDEX
References are included at the end of each chapter.
Classification of Peripheral Neuropathy
Basic Pathological Mechanism
Etiologies of Peripheral Neuropathy
Types of Neuropathies
Symptoms and Signs
Diagnostic Investigations
Nerve Conduction Studies and Needle Electromyography
Laboratory Studies
THE NERVE BIOPSY
Indication for the Nerve Biopsy
Types of Nerve Biopsy
Sural Nerve Biopsy
Sequelae of Nerve Biopsy
Biopsy of Other Nerves
HISTOLOGICAL PROCESSING AND STAINING OF THE BIOPSIED NERVE
Treatment of the Biopsied Nerve
Immediate Care of the Biopsied Nerve
Processing of the Nerve
Paraffin Section Stainings
Frozen Section Stainings
Processing of the Nerve for Semithin and Electron Microscopy Sections
Semithin (0.5 - 1mm) Section Stainings
Nerve Fiber Teasing
Electron Microscope Study
NORMAL NERVE: HISTOLOGY
Age-Related Changes in the Sural Nerve Biopsy
SPECIFIC DIAGNOSTIC PATHOLOGICAL FEATURES OF NERVE BIOPSY
Vasculitis
Amyloid Deposits
Metachromatic Granules
Polyglucosan Body
Onion-Bulb Formation
Inflammatory Cells and Segmental Demyelination
INFLAMMATORY CELLS AND AXONAL DEGENERATION
Noncaseating Granuloma
Necrotizing (Caseating) Granuloma
Giant Axons
Tomacula
Occlusion of Vasa Nervorum
Malignant Cells
IgM Deposits
Segmental Demyelination
Axonal Degeneration
VASCULITIC NEUROPATHY
Vulnerability of the Peripheral Nerve to Vasculitic neuropathy
Clinical, Electromyographic, and Laboratory Features
Diagnostic Sensitivity of Nerve and Muscle Biopsies
Pathology of Vasculitic Neuropathy
Pathogenesis of Vasculitic Neuropathy
Systemic Necrotizing Vasculitides
Vasculitis Associated with Connective Tissue Diseases
Nonsystemic Vasculitic Neuropathy
Vasculitis in Other Diseases
Cases with Vasculitic Neuropathy
INFLAMMATORY DEMYELINATING NEUROPATHY
Pathogenesis of Inflammatory Demyelinating Neuropathies
Guillain-Barré Syndrome (Acute inflammatory Demyelinating Polyneuropathy; AIDP)
Variants of GBS
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Multifocal Motor Neuropathy (MMN)
Multifocal Motor Sensory Demyelinating Neuropathy (MMSDN)
Chronic Sensory Demyelinating Neuropathy (CSDN)
Cases of Inflammatory Demyelinating Neuropathy
IMMUNE-MEDIATED NEUROPATHIES
GM1 Antibody-Positive Neuropathy
Anti-MAG Associated Neuropathy
Neuropathy Associated with Anti-Hu (ANNA 1) Antibody
Neuropathy with Monoclonal Gammopathy
Cases of Immune-Mediated Neuropathy
NEUROPATHIES WITH ABNORMAL DEPOSITS
Amyloid Neuropathy
Metachromatic Leukodystrophy (Sulfatide Lipidosis; Arylsulfatidase Deficiency)
Polyglucosan Body Neuropathy
Fabry's Disease (Alpha-Galactosidase-A Deficiency)
Adrenomyeloneuropathy (AMN)
Cases of Neuropathy with Abnormal Deposit
HEREDITARY NEUROPATHIES
Hereditary Motor and Sensory Neuropathies (HMSN)
Hereditary Sensory Neuropathy
Hereditary Neuropathy to Pressure Palsy (HNPP)
Giant Axonal Neuropathy (GAN)
Friedreich's Ataxia
METABOLIC AND SYSTEMIC NEUROPATHIES
Sarcoid Neuropathy
Sensory Perineuritis
Leprosy
Lymphomatous Neuropathy
Diabetic Neuropathy
Uremic Neuropathy
Alcoholic Neuropathy
Hypothyroid Neuropathy
Vitamin B12 Deficiency Neuropathy
Pyridoxine-Induced Sensory Neuropathy
Polyradiculoneuropathy in Lyme Disease
AIDS Neuropathy
TOXIC NEUROPATHIES
Metal Neuropathies
Drug-Induced Neuropathy
Neuropathy Due to Biological Toxins and Vaccines
Toxic Neuropathy Due to Industrial and Environmental Agents
Epidemic Toxic Inflammatory Neuropathies
Cases of Toxic Neuropathies
INTERPRETATION OF NERVE BIOPSY
INDEX
References are included at the end of each chapter.