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CRISPR-Cas Systems: RNA-mediated Adaptive Immunity in Bacteria and Archaea de Rodolphe Barrangou

CRISPR-Cas Systems: RNA-mediated Adaptive Immunity in Bacteria and Archaea

Editat de Rodolphe Barrangou, John van der Oost
en Limba Engleză Hardback – 14 dec 2012
CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered.
In this book, experts summarize the state of the art in this exciting field.
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Specificații

ISBN-13: 9783642346569
ISBN-10: 3642346561
Pagini: 312
Ilustrații: X, 302 p.
Dimensiuni: 155 x 235 x 22 mm
Greutate: 0.57 kg
Ediția:2013
Editura: Springer Berlin, Heidelberg
Colecția Springer
Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

Discovery and seminal developments in the CRISPR field.- Occurrence, diversity of CRISPR-Cas systems and genotyping implications.-  Evolution and classification of CRISPR-Cas systems and Cas protein families.- Regulation of CRISPR-based immune responses.- crRNA Biogenesis.- Distribution and mechanism of the Type I CRISPR/Cas Systems.- Type II – Streptococcus thermophilus.- Type III CRISPR-Cas Systems and the Roles CRISPR-Cas in Bacterial Virulence.- CRISPR-Cas Systems to Probe Ecological Diversity and Host-Viral Interactions.- Roles of CRISPR in regulation of physiological processes.- Applications of the versatile CRISPR-Cas systems.- CRISPRs in microbial community context.

Textul de pe ultima copertă

CRISPR-Cas is a recently discovered defense system which protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR-Cas immune systems has been identified in at least half of the available prokaryotic genomes. On-going biochemical and functional analyses have resulted in substantial insight into the functions and possible applications of these fascinating systems, although many secrets remain to be uncovered.
In this book, experts summarize the state of the art of this exciting field.

Caracteristici

This is the first book in this exciting field Includes the new CRISPR-Cas systems categorization Written by the leading experts of the CRISPR research community Includes supplementary material: sn.pub/extras