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CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases de Luis María Vaschetto

CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases

Autor Luis María Vaschetto
en Limba Engleză Hardback – 31 ian 2022
The CRISPR-Cas9 genome-editing system is creating a revolution in the science world. In the laboratory, CRISPR-Cas9 can efficiently be used to target specific genes, correct mutations and regulate gene expression of a wide array of cells and organisms, including human cells. CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases is a unique reading material for college students, academicians, and other health professionals interested in learning about the broad range of applications of CRISPR/Cas9 genetic scissors. Some topics included in this book are: the role of the CRISPR/Cas9 system in neuroscience, gene therapy, epigenome editing, genome mapping, cancer, virus infection control strategies, regulatory challenges and bioethical considerations.
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Specificații

ISBN-13: 9780367542863
ISBN-10: 0367542862
Pagini: 268
Ilustrații: 15 Tables, black and white; 3 Illustrations, color; 12 Illustrations, black and white
Dimensiuni: 156 x 234 x 20 mm
Greutate: 1.31 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press

Notă biografică

Luis María Vaschetto received his Doctorate in Biological Sciences from Universidad Nacional de Córdoba (Argentina). He was a postdoctoral researcher at the Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) and a research associate at South Dakota State University (SDSU). His research focuses on understanding the epigenetic mechanisms involved in plant and animal development, as well as their effects on human health and diseases.

Cuprins

1. The CRISPR/Cas9 Genome-editing System: Principles and Applications 2. Recent Applications of CRISPR-Cas9 in Genome Mapping and Sequencing 3. Gene Editing and Genetic Disorders: Ethical and Legal Concerns 4. Political, Regulatory and Ethical Considerations of the CRISPR/Cas Genome Editing Technology 5. CRISPR/Cas and Gene Therapy: An Overview 6. CRISPR and Cancer: From Bench to Clinic 7. The Advances of the CRISPR/Cas9 Technology for Correcting Genetic Disorders: Using Sarcoma as a Model System 8. CRISPR/Cas9 Technology as a Strategy Against Viral Infections 9. CRISPR/Cas9-based Genome and Epigenome Editing in Neuroscience Research 10. Non-viral Alternatives to Delivery of CRISPR-Cas Gene Editing Components 11. CRISPR Medicine: Advance, Progress and Challenges

Recenzii

'Overall, this is an excellent book and a valuable contribution to the burgeoning field of human genome editing. Each chapter is well sourced and has an extensive list of references. Indeed, more than 25 percent of the 259 numbered
pages in the book are devoted to references. This book offers an excellent starting point for exploration of genome editing in humans and is highly recommended.'
- Mark F. Sanders, PhD, UC Davis College of Biological Sciences

Descriere

The CRISPR-Cas9 genome-editing system is creating a revolution in the science world. In the laboratory, CRISPR-Cas9 can efficiently be used to target specific genes, correct mutations and regulate gene expression of a wide array of cells and organisms, including human cells. CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases is a unique reading material for college students, academicians, and other health professionals interested in learning about the broad range of applications of CRISPR/Cas9 genetic scissors. Some topics included in this book are: the role of the CRISPR/Cas9 system in neuroscience, gene therapy, epigenome editing, genome mapping, cancer, virus infection control strategies, regulatory challenges and bioethical considerations.