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Drug Delivery to the Lung

Editat de Hans Bisgaard, Dr Chris O'Callaghan, Gerald C. Smaldone
en Limba Engleză Paperback – 4 noi 2019
This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice.

Examines the behavior of inspired spherical particles in the respiratory tract!

Featuring over 1300 references, drawings, tables, photographs, and micrographs, Drug Delivery to the Lung
  • outlines the history of inhaled medications in the treatment of respiratory disease
  • describes aspects of respiratory structure to inhalation therapy emphasizing developmental changes
  • compares existing in vitro/in vivo correlations for key aerosol modalities with lung model predictions
  • discusses particle diameter measurement, particle size statistics, and aerosol test methods
  • reviews the clinical effects of altering the deposition site of various classes of aerosolized drugs
  • surveys the development of novel, efficient, and convenient nebulizer systems
  • details breath-actuated and spacer devices constructed for children
  • analyzes dry-powder and pressurized metered dose inhalers
  • considers the transition from CFCs to new environmentally friendly chemical propellants
  • and more!
    Giving the clinician an overview of factors essential to understanding drug delivery via nebulization, Drug Delivery to the Lung is a superlative reference for pulmonologists; physiologists; pharmaceutical scientists; immunologists; allergists; analytical, organic, and medicinal chemists and biochemists; chemical, genetic, and process engineers; and medical and graduate school students in these disciplines.
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    Specificații

    ISBN-13: 9780367396879
    ISBN-10: 0367396874
    Pagini: 536
    Dimensiuni: 152 x 229 mm
    Greutate: 0.99 kg
    Ediția:1
    Editura: CRC Press
    Colecția CRC Press
    Locul publicării:Boca Raton, United States

    Public țintă

    Professional Reference

    Cuprins

    The History of Inhaled Drug Therapy

    Notă biografică

    Hans Bisgaard, Chris O'Callaghan, Gerald C. Smaldone

    Descriere

    Chris O'Callaghan, Ola Nerbrink, and Mika T. Vidgren

    Basic Principles of Particle Behavior in the Human Respiratory Tract
    Joachim Heyder and Magnus Svartengren

    Structure and Function of the Respiratory System: Developmental Aspects and Their Relevance to Aerosol Therapy
    Janet Stocks and Alison A. Hislop

    In Vitro Testing of Pharmaceutical Aerosols and Predicting Lung Deposition from In Vitro Measurements
    Andy Clark and Lars Borgström

    Factors Affecting the Clinical Outcome of Aerosol Therapy
    Eric Derom and Lars Thorsson

    In Vivo Measurements of Lung Dose
    Mark L. Everard and Myrna B. Dolovich

    Targeting the Lungs with Therapeutic Aerosols