Drug Discovery Strategies and Methods
Autor Alexandros Makriyannis, Diane Biegelen Limba Engleză Hardback – 4 noi 2003
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Specificații
ISBN-13: 9780824706913
ISBN-10: 0824706919
Pagini: 348
Dimensiuni: 210 x 280 x 24 mm
Greutate: 0.61 kg
Ediția:New.
Editura: CRC Press
Colecția CRC Press
Locul publicării:Boca Raton, United States
ISBN-10: 0824706919
Pagini: 348
Dimensiuni: 210 x 280 x 24 mm
Greutate: 0.61 kg
Ediția:New.
Editura: CRC Press
Colecția CRC Press
Locul publicării:Boca Raton, United States
Public țintă
ProfessionalCuprins
1 Protein Crystallography in Structure based Drug Design, 2 SRS Homology-2 Domains and Structure-Based, Small Molecule Library Approaches to Drug Discovery, 3Three-Dimensional Structure of the Inhibited Catalytic Domain of Human Stromelysin-1 by Heteronuclear NMR Spectroscopy, 4 Cannabinergics: Old and New Therapeutic Possibilities, 5 Development of PET and SPECT Radioligands for Cannabinoid Receptors, 6 Structural and Pharmacological Aspects of Peptidomimetics, 7 Linkers and Resins for Solid-Phase Synthesis, 8 Allosteric Modulation of G Protein -Coupled Receptors: Implications for Drug Action 9 Protein Misfolding and Neurodegenerative Disease: Therapeutic Opportunities 10 Uncoating and Adsorption Inhibitors of Rhinovirus Replication, 11 Profiles of Prototype Antiviral Agents Interfering with the Initial Stages of HIV Infection
Notă biografică
Alexandros Makriyannis University of Connecticut, Storrs, Connecticut, U.S.A.
Descriere
This volume addresses challenges encountered during the discovery of new pharmaceutical candidates including the use of cutting-edge techniques utilized in drug design and development.