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Drug Resistance in Cancer Therapy: Cancer Treatment and Research, cartea 48

Editat de Robert F. Ozols
en Limba Engleză Hardback – 31 aug 1989
Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfor­ tunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung can­ cer, genitourinary cancer, and pediatric oncology; second, by asking emi­ nent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
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Specificații

ISBN-13: 9780792302445
ISBN-10: 0792302443
Pagini: 210
Ilustrații: XIV, 210 p.
Dimensiuni: 155 x 235 x 14 mm
Greutate: 0.5 kg
Ediția:1989
Editura: Springer Us
Colecția Springer
Seria Cancer Treatment and Research

Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

1. Drug resistance: The clinical problem.- 2. Mathematical models of drug resistance and chemotherapy effects.- 3. Multidrug resistance in human tumors.- 4. Structure and function of P—glycoprotein.- 5. Anthracycline resistance.- 6. Circumvention of drug resistance with calcium channel blockers and monoclonal antibodies.- 7. P—glycoprotein in breast cancer.- 8. Phosphoprotein, protein kinase C, and second-messenger system changes in human multidrug-resistant cancer cells.- 9. Alkylating agent resistance.- 10. Mechanisms of resistance to cisplatin and alkylating agents.- 11. Glutathione S—transferase and drug resistance.- 12. Tumor cell drug and radiation resistance: Does an interrelationship exist?.

Recenzii

`This book would be a helpful text for basic researchers, clinical investigators, and medical housestaff. It is well written and can be read in a relatively short period.'
Breast Cancer Research and Treatment, 19, 1991
` The book is an exciting survey of the potential application of laboratory data. It is a good example of interdisciplinary research collaboration. It is recommended reading for those engaged in the development of new treatment strategies.'
Oncology, 48/1