Duchenne Muscular Dystrophy: Advances in Therapeutics: Neurological Disease and Therapy
Editat de Jeffrey S. Chamberlain, Thomas A. Randoen Limba Engleză Hardback – 27 feb 2006
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Specificații
ISBN-13: 9780824723255
ISBN-10: 0824723252
Pagini: 496
Ilustrații: 75 b/w images, 19 tables and 32 halftones
Dimensiuni: 152 x 229 x 28 mm
Greutate: 0.79 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Seria Neurological Disease and Therapy
Locul publicării:Boca Raton, United States
ISBN-10: 0824723252
Pagini: 496
Ilustrații: 75 b/w images, 19 tables and 32 halftones
Dimensiuni: 152 x 229 x 28 mm
Greutate: 0.79 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Seria Neurological Disease and Therapy
Locul publicării:Boca Raton, United States
Public țintă
Professional and Professional Practice & DevelopmentCuprins
Clinical Overview. The Functional Biology of Dystrophin. Duchenne Muscular Dsytrophy and Becker Muscular Dystrophy: Diagnostic Principles. Mutation Detection. Protein Studies. Medical Management. Rehabilitation Management. A Review of Current Practice and Clinical Outcomes. Therapeutic Principles and Challenges. Experimental Pharmacologic Therapies. Utrophin: The Intersection between Pharmacological and Genetic Therapy. Regenerative Therapy. Cellular-Mediated Delivery: The Intersection between Regenerative Medicine and Genetic Therapy. Oligonucleotide-Mediated Rxon Skipping and Gene Editing. Intravascular Delivery of Naked DNA. Adenoviral-Mediated Gene Therapy. Retroviridae-based Gene Transfer Vectors. Gene Therapy Using Adeno-Associated Viral Vectors. Regional and Systemic Gene Delivery using Viral Vectors.
Notă biografică
Jeffrey S. Chamberlain, Thomas A. Rando
Descriere
Duchenne Muscular Dystrophy (DMD) is one of the most prevalent genetic disorders of childhood for which there is no cure. This authoritative guide provides a clear overview of the clinical, genetic, and pathophysiological aspects of the disease in the context of emerging therapeutic modalities. The only available source on the subject, this reference emphasizes the importance of accurate diagnosis, carrier detection, and genetic counseling, and supplies state-of-the-art information on pharmacological interventions, regenerative medicine, and gene therapy.