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Early Phase Cancer Immunotherapy: Current Cancer Research

Editat de Sandip Pravin Patel, Razelle Kurzrock
en Limba Engleză Hardback – 10 noi 2017
This volume, a state-of-the-art review of early phase clinical trials for cancer immunotherapy, discusses biomarker selection, combinatorial strategies and their safety or toxicity, determination of Phase 2 dosing, endpoints in the setting of radiographic pseudoprogression, histology selection, and novel immunotherapeutics as they relate to early phase cancer immunotherapy.
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Specificații

ISBN-13: 9783319637563
ISBN-10: 3319637568
Pagini: 331
Ilustrații: XI, 331 p. 24 illus., 15 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.66 kg
Ediția:1st ed. 2018
Editura: Springer International Publishing
Colecția Springer
Seria Current Cancer Research

Locul publicării:Cham, Switzerland

Cuprins

Chapter 1 Primer on Cancer Immunotherapy and the Targeting of Native Proteins.- Chapter 2 Pharmacokinetics and Pharmacodynamics of Immunotherapy.- Chapter 3 Immunotherapeutic Biomarkers and Selection Strategies.- Chapter 4 Radiographic Evaluation of Immunotherapy.- Chapter 5 Cellular Therapy.- Chapter 6 Combinatorial Checkpoint Blockade Immunotherapy and Radiation.- Chapter 7 Early Phase Cancer Immunotherapy.- Chapter 8 Immune Checkpoint Combinations with Inflammatory Pathway Modulators.- Chapter 9 Combinations of Genomically and Immune-Targeted Therapies in Early-Phase Clinical Trials.- Chapter 10 Thoracic Immunotherapy.

Notă biografică

Razelle Kurzrock, MD, is Senior Deputy Director for Clinical Science, Chief, Division of Hematology & Oncology, Murray Professor of Medicine, Director, Center for Personalized Cancer Therapy & Clinical Trials Office, University of California, San Diego.
Sandip Patel, MD, is Assistant Professor, Cancer Immunotherapy Program, Experimental Therapeutics (Phase 1 Program), Thoracic Oncology, Division of Hematology & Oncology and Center for Personalized Cancer Therapy, UC San Diego Moores Cancer Center.

Textul de pe ultima copertă

This volume, a state-of-the-art review of early phase clinical trials for cancer immunotherapy, discusses biomarker selection, combinatorial strategies and their safety or toxicity, determination of Phase 2 dosing, endpoints in the setting of radiographic pseudoprogression, histology selection, and novel immunotherapeutics as they relate to early phase cancer immunotherapy.

Caracteristici

Focuses on a state-of-the-art review of early phase clinical trials for cancer immunotherapy Discusses about biomarker selection and combinatorial strategies Discusses about safety/toxicity determination of Phase 2 dosing, endpoints in the setting of psuedoprogession and histology selection as they relate to early phase cancer immunotherapy Features chapters written by internationally-known experts in the field