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Enzyme Cascade Design and Modelling

Editat de Selin Kara, Florian Rudroff
en Limba Engleză Paperback – 25 feb 2022
This book provides a comprehensive overview of the recent developments achieved in the field of chemo/enzymatic cascades with topics spanning from design (in vitro and in vivo) to kinetic- and process modelling as well as process control. Opportunities and challenges of building multi-step chemo/enzymatic reactions are discussed, whereby the latter are critically assessed in each chapter and methods to ease the implementation are explored. Both, multi-enzymatic cascades and chemo-enzymatic cascades are presented with the motivation of combining the strengths of these two worlds (e.g. selectivity, activity and robustness) not neglecting the obstacles and challenges of such endeavour. Furthermore, the use of non-conventional media for catalytic cascade reactions, recent achievements and potential for future developments in a technical environment are addressed.   

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Specificații

ISBN-13: 9783030657208
ISBN-10: 3030657205
Pagini: 181
Ilustrații: VII, 181 p. 103 illus., 61 illus. in color.
Dimensiuni: 178 x 254 mm
Ediția:1st ed. 2021
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

Preface.- Chapter 1: Introduction.- Chapter 2: Enzyme Cascade Design – Retrosynthesis Approach.- Chapter 3 : Multi-Enzymatic Cascades in vitro.- Chapter 4: Multi-Enzymatic Cascades in vivo.- Chapter 5: Chemo-Enzymatic Cascades.- Chapter 6: Enzyme Cascade Kinetic Modelling.- Chapter 7: Enzyme Cascade Reaction Engineering.- Chapter 8: Enzyme Cascade Process Design and Modelling.- Chapter 9: Enzyme Cascade Reaction Monitoring And Control.- Chapter 10: Cascade reactions in non-conventional media.- Chapter 11: Perspectives.

Notă biografică

Prof. Dr. Selin Kara, Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark

Assoc. Prof. Dr. Florian Rudroff, Institute of Applied Synthetic Chemistry, Vienna University of Technology, Vienna, Austria   



Textul de pe ultima copertă

This book provides a comprehensive overview of the recent developments achieved in the field of chemo/enzymatic cascades with topics spanning from design (in vitro and in vivo) to kinetic- and process modelling as well as process control. Opportunities and challenges of building multi-step chemo/enzymatic reactions are discussed, whereby the latter are critically assessed in each chapter and methods to ease the implementation are explored. Both, multi-enzymatic cascades and chemo-enzymatic cascades are presented with the motivation of combining the strengths of these two worlds (e.g. selectivity, activity and robustness) not neglecting the obstacles and challenges of such endeavour. Furthermore, the use of non-conventional media for catalytic cascade reactions, recent achievements and potential for future developments in a technical environment are addressed.

Caracteristici

Creates the basis for pathway design via the concept of ‘biocatalytic retrosynthesis’ Enhances the readers’ understanding on kinetic modelling and reaction engineering Introduces process design, process modelling, monitoring and control of catalytic cascades Discusses both multi-enzymatic and chemo-enzymatic cascades Provides an outlook on industrial applications and future developments