Enzyme Inhibition in Drug Discovery and Development – The Good and the Bad
Autor C Luen Limba Engleză Hardback – 25 ian 2010
With chapters written by over fifty leading experts in their fields, Enzyme Inhibition in Drug Discovery and Development fosters a cross-fertilization of pharmacology, drug metabolism, pharmacokinetics, and toxicology by understanding the "good" inhibitions--desirable pharmacological effects--and "bad" inhibitions--drug-drug interactions and toxicity. The book discusses:
- The drug discovery process, including drug discovery strategy, medicinal chemistry, analytical chemistry, drug metabolism, pharmacokinetics, and safety biomarker assessment
- The manipulations of drug metabolizing enzymes and transporters as well as the negative consequences, such as drug-drug interactions
- The inhibition of several major drug target pathways, such as the GPCR pathway, the NFkB pathway, and the ion channel pathway
Preț: 1439.30 lei
Preț vechi: 1515.05 lei
-5% Nou
Puncte Express: 2159
Preț estimativ în valută:
275.45€ • 286.12$ • 228.80£
275.45€ • 286.12$ • 228.80£
Carte tipărită la comandă
Livrare economică 01-15 februarie 25
Preluare comenzi: 021 569.72.76
Specificații
ISBN-13: 9780470281741
ISBN-10: 047028174X
Pagini: 868
Dimensiuni: 167 x 244 x 45 mm
Greutate: 1.27 kg
Editura: Wiley
Locul publicării:Hoboken, United States
ISBN-10: 047028174X
Pagini: 868
Dimensiuni: 167 x 244 x 45 mm
Greutate: 1.27 kg
Editura: Wiley
Locul publicării:Hoboken, United States
Public țintă
Pharmaceutical industry researchers in drug metabolism, pharmacokinetics, toxicology, pharmacology, ADME, regulatory affairs personnel, academics in any of the above disciplinesNotă biografică
Cuprins
Descriere
This book covers the science and approaches of enzyme inhibition applied in drug discovery and drug development, including both pharmacology and pharmacokinetic aspects of enzyme inhibition.