Epigenetic Technological Applications
Editat de Yujun George Zhengen Limba Engleză Hardback – 27 iul 2015
- Discusses technologies that are critical for epigenetic research and application
- Includes epigenetic applications for state-of-the-art technologies
- Contains a global perspective on the future of epigenetics
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Specificații
ISBN-13: 9780128010808
ISBN-10: 0128010800
Pagini: 516
Ilustrații: 50
Dimensiuni: 191 x 235 x 30 mm
Greutate: 1.34 kg
Editura: ELSEVIER SCIENCE
ISBN-10: 0128010800
Pagini: 516
Ilustrații: 50
Dimensiuni: 191 x 235 x 30 mm
Greutate: 1.34 kg
Editura: ELSEVIER SCIENCE
Public țintă
Researchers in genetics, biology, biochemistry, and biophysics, and pharmaceutical and biotechnological industry scientistsCuprins
Preface1. Introduction of the Epigenetic Technologies2. Technologies for the Measurement and Mapping of Genomic 5-methylcytosine and 5-hydroxymethylcytosine3. Technologies to Map DNA 5hC and 5fC and 5caC4. Application of Mass Spectrometry in Translational Epigenetics5. Techniques Analyzing Chromatin Modifications at Specific Single Loci6. Comprehensive Analysis of Mammalian Linker-histone Variants and Their Mutants7. Crystallography-based Mechanistic Insights into Epigenetic Regulation8. Chemical and Genetic Approaches to Study Histone Modifications9. Peptide Microarrays for Profiling of Epigenetic Targets10. Current Methods for Methylome Profiling11. Bioinformatics and Biostatistics for Mining Epigenetic Disease Markers and Targets12. Computational Modeling to Elucidate Molecular Mechanisms of Epigenetic Memory13. DNA Methyltransferase Inhibitors for Cancer Therapy14. Histone Acetyltransferases: Enzymes, Assays, and Inhibitors15. In Vitro Histone Deacetylase Activity Screening: Making a Case for Better Assays 16. Enzymatic Assays of Histone Methyltransferase Enzymes17. Histone Methyltransferase Inhibitors for Cancer Therapy18. Discovery of Histone Demethylase Inhibitors19. Fluorescent Technologies in Studying Dynamics of Histone Modification20. Animal Model Study of Epigenetic Inhibitors