This title includes a number of Open Access chapters.


This important book explores recent research by experts in the field pertaining to the role played by genetic factors in human pathology. A range of perspectives creates a well-rounded picture, including:

• host-pathogen interactions



• causal relationships between genes and the environment



• the effects of environmental chemicals on gene expression



• DNA methylation

The book also covers the analysis and provides models for understanding the epigenetics-pathology connection.




This book is designed for use by senior undergraduate and graduate students from several disciplines such as general, molecular, cellular biology, genetics, genomics, proteomics, and bioinformatics. It will also serve as a reference book for existing researchers and new investigators entering this rather unexplored field.