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Epigenetics in Cardiac Disease: Cardiac and Vascular Biology

Editat de Johannes Backs, Timothy A. McKinsey
en Limba Engleză Paperback – 30 apr 2018
This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field. Edited and written by internationally respected experts, it addresses the needs of professors, students and researchers working in the fields of cardiac biology and epigenetics.
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Specificații

ISBN-13: 9783319823607
ISBN-10: 3319823604
Pagini: 316
Ilustrații: VIII, 316 p. 34 illus., 24 illus. in color.
Dimensiuni: 155 x 235 mm
Ediția:Softcover reprint of the original 1st ed. 2016
Editura: Springer International Publishing
Colecția Springer
Seria Cardiac and Vascular Biology

Locul publicării:Cham, Switzerland

Cuprins

1. Jim Davie (backup - Ed Seto; Moffitt, Florida), U. of Manitoba: General Review of Epigenetics.- 2. Benoit Bruneau (backup - Kunhua Song; U. of Colorado), UCSF: Chromatin Remodeling in Cardiac Progenitor Cells, Cardiac Development.- 3. Eric Verdin, UCSF: Epigenetics and Metabolism.- 4. Eileen Furlong, EMBL – Heidelberg: Computational Epigenetics.- 5. Eric Olson (backup - Kook; Korea), UT Southwestern: Role of Class I HDACs in the Heart/Metabolism.- 6. Timothy McKinsey , U. of Colorado: HDACs and HATs in Cardiopulmonary Remodeling.- 7. Johannes Backs, U. of Heidelberg: HDAC Signaling Networks in HF.- 8. Jun Sadoshima , New Jersey: Sirtuins and HF.- 9. Zhi-Ping Liu, UT Southwestern: Histone Methylation in Heart Failure.- 10. C.P. Chang (backup - Bultman; North Carolina), Stanford: Chromatin Remodeling in Heart Failure.- 11. Sap Halder, Case Western: pTEFb and BET Proteins in Heart Failure.- 12. Norbert Frey, Kiel, Germany: Long Non-Coding RNAs in Heart Failure.- 13. Assam El-Osta, Melbourne, Australia: Chromatin Marks in Heart Failure.- 14. Roger Foo (backup - Meder; U. of Heidelberg), Singapore: DNA Methylation in Heart Failure.- 15. Joe Hill, UT Southwestern: HDACs and Autophagy in Heart Failure.- 16. Elisabeth Zeisberg (Göttingen) , Gottingen University: Epigenetics Regulation of Fibrosis.- 17. C. Choudhary, U. of Copenhagen: Mass Spectrometry Analysis of the Acetylome.

Notă biografică

Prof. Johannes Backs, MD Research Unit Cardiac Epigenetics University of Heidelberg Im Neuenheimer Feld 410 69221 Heidelberg Germany johannes.backs@med.uni-heidelberg.de

Prof. Timothy A. McKinsey, PhD Department of Medicine/Division of Cardiology University of Colorado Denver 12700 E 19th Avenue Aurora CO 80045 USA timothy.mckinsey@ucdenver.edu

Textul de pe ultima copertă

This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field. Edited and written by internationally respected experts, it addresses the needs of professors, students and researchers working in the fields of cardiac biology and epigenetics.

Caracteristici

The first book dedicated to epigenetic regulation in cardiac diseases Provides insight into the complexity of histon and DNA modifications that contribute to cardiac development and the pathogenesis of cardiac diseases Offers a broad overview on the topic and discusses the latest advances in the field