Ferroptosis in Health and Disease
Editat de Daolin Tangen Limba Engleză Hardback – 28 oct 2023
Readers will gain an understanding of the multiple levels, on which this special cell death is regulated. Hence, the contributions will take a closer look at epigenetic, transcriptional, posttranscriptional and posttranslational layers. Among the described regulators and transcription factors are GPX4, ACSL4 and NFE2L2.
This edited volume collects reviews related to current knowledge on the integrated molecular machinery of ferroptosis, thereby also describing how dysregulated ferroptosis is involved in human diseases.
| Toate formatele și edițiile | Preț | Express |
|---|---|---|
| Paperback (1) | 930.28 lei 6-8 săpt. | |
| Springer International Publishing – 23 oct 2020 | 930.28 lei 6-8 săpt. | |
| Hardback (1) | 1372.35 lei 6-8 săpt. | |
| Springer International Publishing – 28 oct 2023 | 1372.35 lei 6-8 săpt. |
Preț: 1372.35 lei
Preț vechi: 1673.60 lei
-18% Nou
Puncte Express: 2059
Preț estimativ în valută:
262.72€ • 273.09$ • 217.83£
262.72€ • 273.09$ • 217.83£
Carte tipărită la comandă
Livrare economică 08-22 februarie 25
Preluare comenzi: 021 569.72.76
Specificații
ISBN-13: 9783031391705
ISBN-10: 3031391705
Pagini: 490
Ilustrații: VIII, 490 p. 54 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.87 kg
Ediția:2nd ed. 2023
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland
ISBN-10: 3031391705
Pagini: 490
Ilustrații: VIII, 490 p. 54 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.87 kg
Ediția:2nd ed. 2023
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland
Cuprins
Notă biografică
Daolin Tang
Dr Tang’s work chiefly focuses on designing and conducting molecular, cellular, and animal studies to investigate the mechanisms of damage-associated molecular pattern molecule (DAMP) release and activity in autophagy and cell death, and to evaluate novel drug candidates for the treatment of various inflammatory diseases, including cancer. His past contributions to biomedical science include the initial description of the role of high-mobility group box 1 (HMGB1), a classical DAMP, in autophagy. His recent contributions to DAMP biology include the identification of a novel function and activity of HMGB1 in infection and sterile inflammation. More recently, he has also identified a number of regulators of necroptosis, ferroptosis, pyroptosis, and alkaliptosis. In summary, Dr Tang is an outstanding investigator with a proven track record of innovation and achievement in the fields of DAMP, autophagy, and cell death.
Dr Tang’s work chiefly focuses on designing and conducting molecular, cellular, and animal studies to investigate the mechanisms of damage-associated molecular pattern molecule (DAMP) release and activity in autophagy and cell death, and to evaluate novel drug candidates for the treatment of various inflammatory diseases, including cancer. His past contributions to biomedical science include the initial description of the role of high-mobility group box 1 (HMGB1), a classical DAMP, in autophagy. His recent contributions to DAMP biology include the identification of a novel function and activity of HMGB1 in infection and sterile inflammation. More recently, he has also identified a number of regulators of necroptosis, ferroptosis, pyroptosis, and alkaliptosis. In summary, Dr Tang is an outstanding investigator with a proven track record of innovation and achievement in the fields of DAMP, autophagy, and cell death.
Textul de pe ultima copertă
This updated and expanded volume gives new insights on ferroptosis – an iron-dependent form of non-apoptotic cell death. The collection of chapters discusses the two major pathways through which ferroptosis can occur: the extrinsic or transporter-dependent pathway and the intrinsic or enzyme-regulated pathway.
Readers will gain an understanding of the multiple levels, on which this special cell death is regulated. Hence, the contributions will take a closer look at epigenetic, transcriptional, posttranscriptional and posttranslational layers. Among the described regulators and transcription factors are GPX4, ACSL4 and NFE2L2.
This edited volume collects reviews related to current knowledge on the integrated molecular machinery of ferroptosis, thereby also describing how dysregulated ferroptosis is involved in human diseases.
Readers will gain an understanding of the multiple levels, on which this special cell death is regulated. Hence, the contributions will take a closer look at epigenetic, transcriptional, posttranscriptional and posttranslational layers. Among the described regulators and transcription factors are GPX4, ACSL4 and NFE2L2.
This edited volume collects reviews related to current knowledge on the integrated molecular machinery of ferroptosis, thereby also describing how dysregulated ferroptosis is involved in human diseases.
Caracteristici
Offers updates for some original chapters and new contributions
Discusses the effects of ferroptosis cell death on metabolism
Explores the relevance of ferroptosis cell death for human diseases
Discusses the effects of ferroptosis cell death on metabolism
Explores the relevance of ferroptosis cell death for human diseases