Gangrene is a major health concern and can cause adverse effects in its various clinical manifestations which result in considerable mass of body tissues dying due to some or the other cause. This book provides the readers with details on latest advancements and research in the field of gangrene management. It undertakes dialogues and discussions on clinical, physiological, bacteriological and other aspects of this method. Complicated challenges related to diabetic and non-diabetic gangrene management have also been extensively discussed. Specific interest has been taken to analyze current trends, as well as epidemiology of gangrene as a serious and potentially fatal complication.