This is a comprehensive book which provides up-to-date detailed information regarding sepsis and septic shock. Even though extensive progress in the handling of severe sepsis and septic shock has been made, it is still one of the foremost causes of deaths around the world. Certain experts regard it as one of the most challenging issues due to its varied presentations and diverse complexities. Dedicated researchers from around the globe have contributed important information on this lethal condition. It is hoped that the hard work put in by the researchers will lead to the compilation of a useful source of guidance for continuing the intense work and interest in patient-care.