Gap Junctions in Development and Disease
Editat de Elke Winterhageren Limba Engleză Hardback – 18 iul 2005
Although the question of why some mutations in gap-junction proteins lead to specific phenotypes remains to be answered, the reviews in this book provide an intriguing insight into the future direction of this research field.
Toate formatele și edițiile | Preț | Express |
---|---|---|
Paperback (1) | 786.18 lei 38-44 zile | |
Springer Berlin, Heidelberg – 13 oct 2010 | 786.18 lei 38-44 zile | |
Hardback (1) | 931.40 lei 6-8 săpt. | |
Springer Berlin, Heidelberg – 18 iul 2005 | 931.40 lei 6-8 săpt. |
Preț: 931.40 lei
Preț vechi: 1135.86 lei
-18% Nou
Puncte Express: 1397
Preț estimativ în valută:
178.25€ • 185.16$ • 148.06£
178.25€ • 185.16$ • 148.06£
Carte tipărită la comandă
Livrare economică 04-18 februarie 25
Preluare comenzi: 021 569.72.76
Specificații
ISBN-13: 9783540261568
ISBN-10: 3540261567
Pagini: 300
Ilustrații: XVII, 279 p. 47 illus., 10 illus. in color.
Dimensiuni: 155 x 235 x 24 mm
Greutate: 0.59 kg
Ediția:2005
Editura: Springer Berlin, Heidelberg
Colecția Springer
Locul publicării:Berlin, Heidelberg, Germany
ISBN-10: 3540261567
Pagini: 300
Ilustrații: XVII, 279 p. 47 illus., 10 illus. in color.
Dimensiuni: 155 x 235 x 24 mm
Greutate: 0.59 kg
Ediția:2005
Editura: Springer Berlin, Heidelberg
Colecția Springer
Locul publicării:Berlin, Heidelberg, Germany
Public țintă
ResearchDescriere
Communication between cells via intercellular channels – gap junctions – appears essential to certain developmental processes and appropriate organ function. Gap Junctions in Development and Disease aims to describe the molecular events underlying impaired development and disease. Beginning with a comprehensive review of various mouse and human genes encoding the channel-forming connexins, later chapters describe several connexin mutations associated with human diseases such as hereditary deafness and female infertility. Erroneous signaling mediated by the interaction of mutant connexins with other proteins, thought to be responsible for dysfunction of organs such as heart, muscle, brain, skin, lens, placenta, and endocrine tissue in both mice and men, is also addressed.
Although the question of why some mutations in gap-junction proteins lead to specific phenotypes remains to be answered, the reviews in this book provide an intriguing insight into the future direction of this research field.
Although the question of why some mutations in gap-junction proteins lead to specific phenotypes remains to be answered, the reviews in this book provide an intriguing insight into the future direction of this research field.
Cuprins
1 Connexin and Pannexin Genes in the Mouse and Human GenomeKlaus Willecke, Jürgen Eiberger and Julia von Maltzahn 2 Essential Role of Gap Junctions during Development and Regeneration of Skeletal MuscleJulia von Maltzahn and Klaus Willecke 3 Connexins in Cardiac Development: Expression, Role, and Transcriptional ControlDaniel B. Gros, S. Alcoléa, L. Dupays, S. Meysen, L. Miquerol, M. Théveniau-Ruissy, BEJ Teunissen, MFA Bierhuizen 4 Gap Junction and Connexin Remodelling in Human Heart DiseaseNicholas J. Severs, Emmanuel Dupont, Riyaz Kaba and Neil Thomas 5 Gap Junction Expression in Brain Tissues with Focus on DevelopmentRolf Dermietzel and Carola Meier 6 Connexins Responsible for Hereditary Deafness - The Tale UnfoldsMartine Cohen-Salmon, Francisco J. del Castillo, and Christine Petit 7 Human Connexins in Skin Development and Skin DisordersGabriele Richard 8 Intercellular Communication in Lens Development and DiseaseAdam M. DeRosa, Francisco J. Martinez-Wittinghan, Richard T. Mathias, Thomas W. White 9 Connexin Modulators of Endocrine FunctionPhilippe Klee, Nathalie Boucard, Dorothée Caille, José Cancela, Anne Charollais, Eric Charpantier, Laetitia Michon, Céline Populaire, Manon Peyrou, Rachel Nlend Nlend, Laurence Zulianello, Jacques-Antoine Haefliger, and Paolo Meda 10 Roles of Gap Junctions in Ovarian Folliculogenesis: Implications for Female InfertilityGerald M. Kidder 11 Placental Connexins of Mice and MenCaroline Dunk, Mark Kibschull, Alexandra Gellhaus, Elke Winterhager and Stephen Lye 12 Connexins in Growth Control and CancerChristian C. Naus, Gary S. Goldberg and Wun Chey Sin
Textul de pe ultima copertă
The main objective of Gap Junctions in Development and Disease is to describe the molecular events that cause impairments in development and disease. Communication between cells via intercellular channels, so called gap junctions, appears to be essential for certain developmental processes and appropriate organ function. Starting with a comprehensive review of the various mouse and human genes encoding the channel-forming protein connexin, further chapters describe the most important connexin mutations that lead to diseases such as hereditary deafness and female infertility in humans. Erroneous signaling mediated via connexin-protein interactions, thought to be responsible for disfunction of organs such as heart, muscle, brain, skin, lens, placenta, and endocrine tissue in mice and men, is also addressed.
Although the question why some of the mutations in gap-junction proteins lead to a specific phenotype remains to be answered, the reviews in this book give an intriguing outlook on the future direction of this research field.
Although the question why some of the mutations in gap-junction proteins lead to a specific phenotype remains to be answered, the reviews in this book give an intriguing outlook on the future direction of this research field.
Caracteristici
First book to connect changes of gap junction proteins with disease
Brilliant color illustrations
Contributions by experienced authors
Includes supplementary material: sn.pub/extras
Brilliant color illustrations
Contributions by experienced authors
Includes supplementary material: sn.pub/extras