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Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders de Anantha Shekhar

Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders: Progress in Brain Research, cartea 241

Anantha Shekhar
en Limba Engleză Hardback – 15 noi 2018
Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders, Volume 241 provides the most recent information on the animal model systems that are available to study different forms of autism spectrum disorders. In addition to genetically engineered animals that uniquely model genetic forms of ASD, this volume also provides detailed chapters on a variety of specific topics, including An overview of genetic models of ASDs, Phenotypic modeling of ASD symptoms, Molecular mechanisms of NF1 model of ASD symptoms, Ube3a gene dosage disorders: molecular and circuit mechanisms of ASD, Circuit dysfunctions in ASD models, ERK signaling in genetic models of ASD, and more.


  • Presents a timely, comprehensive assessment of the field
  • Includes helpful summaries on current knowledge, gaps and future directions in autism research
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Specificații

ISBN-13: 9780444641946
ISBN-10: 0444641947
Pagini: 232
Dimensiuni: 191 x 235 mm
Greutate: 0.62 kg
Editura: ELSEVIER SCIENCE
Seria Progress in Brain Research

Public țintă

The audience for this volume are basic researchers, preclinical neuroscientists and clinical/translational researchers developing novel diagnostics and therapeutics for autism and other neurodevelopmental disorders. This would also be a great primer for graduate students and post-docs working in this field

Cuprins

1. Overview of genetic models of autism spectrum disordersJheel Patel, Jodi Lukkes and Anantha Shekhar2. Neurofibromatosis type 1 as a model system to study molecular mechanisms of autism spectrum disorder symptomsAndrei I. Molosh and Anantha Shekhar3. ERK/MAPK signaling and autism spectrum disordersJoseph Vithayathil, Joanna Pucilowska and Gary E. Landreth4. From bedside to bench and back: Translating ASD modelsDrozd H. P., S.F. Karathanasis S. F., Molosh A, Lukkes J, D. Wade Clapp and A. Shekhar5. Studying child development in genetic models of ASDShruti Garg and Jonathan Green6. Measurement considerations in pediatric research on autism spectrum disordersKarin S. Walsh and Srishti Rau