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Genetic Recombination in Cancer

Autor Gajanan V. Sherbet
en Limba Engleză Hardback – 23 iul 2003
Genetic recombination is a process of combining genes that leads to the generation of cell variants that possess different characteristics. This process is important to the evolution of a species and to embryonic growth and differentiation. However, this process can also lead to the development of abnormal, cancerous cells. This book reviews the role of genetic recombination in the generation of various cancers and how genetic alterations have been or could be employed to elicit clinically useful information.

* Provides detailed discussion of the genetic mechanisms that result in the generation of normal and abnormal cells* Examines the role of genetic recombination in cancer including cancer invasion and metastasis* Information is presented in a manner that is useful and accessible to everyone from graduate students to established cancer researchers
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Specificații

ISBN-13: 9780126398816
ISBN-10: 012639881X
Pagini: 264
Dimensiuni: 152 x 229 x 19 mm
Greutate: 0.54 kg
Ediția:New.
Editura: ELSEVIER SCIENCE

Public țintă

Researchers, post-graduate and graduate students in molecular medicine, genetics, cancer biology and molecular biology.

Cuprins

Genetic Integrity, DNA Repair and RecombinationReplication Error (RER) and Genetic InstabilityDNA Repeats, Genetic Recombination and the Pathogenesis of Genetic DisordersChromosomal Recombination in CancerChromosomal Translocation and its Phenotypic OutcomeDNA Methylation and Genetic InstabilityTelomeric DNA and Genetic Instability