Cantitate/Preț
Produs
Total produse
Vezi coșul
Genetics of Colorectal Cancer de John D. Potter

Genetics of Colorectal Cancer: Cancer Genetics

Editat de John D. Potter, Noralane M. Lindor
en Limba Engleză Hardback – 8 dec 2008
Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 109573 lei  6-8 săpt.
  Springer – 9 noi 2010 109573 lei  6-8 săpt.
Hardback (1) 110282 lei  6-8 săpt.
  Springer – 8 dec 2008 110282 lei  6-8 săpt.

Din seria Cancer Genetics

  • 5% Male Reproductive Cancers: Epidemiology, Pathology and Genetics
    Preț: 141316 lei
  • 5% The Role of Genetics in Breast and Reproductive Cancers
    Preț: 141316 lei
  • 5% Cancer Genome and Tumor Microenvironment
    Preț: 142141 lei
  • 5% Molecular Genetics of Liver Neoplasia
    Preț: 141645 lei
  • 5% Genetics of Melanoma
    Preț: 72321 lei

Preț: 110282 lei

Preț vechi: 116086 lei
-5% Nou

Puncte Express: 1654
Preț estimativ în valută:
21105€ • 21773$ • 17862£

Carte tipărită la comandă

Livrare economică 05-19 martie

 Adaugă în coș

Wish list
Gift list
Am citit!
Adaugă în listă
Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9780387095677
ISBN-10: 0387095675
Pagini: 309
Ilustrații: XI, 309 p.
Dimensiuni: 155 x 235 x 19 mm
Greutate: 0.63 kg
Ediția:2009
Editura: Springer
Colecția Springer
Seria Cancer Genetics

Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

Epidemiology and Models of Colorectal Cancer.- Colorectal Cancer: Epidemiology.- Mouse Models of Intestinal Cancer.- Pathways to Colorectal Cancer.- The Chromosomal-Instability Pathway and APC Gene Mutation in Colorectal Cancer.- DNA Methylation in Colorectal Cancer: Multiple Facets of Tumorigenesis.- Pathways and Pathology.- Germline Susceptibility – Mendelian and Other Syndromes.- Familial Adenomatous Polyposis.- DNA Mismatch Repair and Lynch Syndrome.- Additional Syndromes with Hereditary Predisposition to Colorectal Cancer.- Familial Colorectal Cancer Type X.- Families with Serrated Neoplasia of the Colon.- Peutz–Jeghers Syndrome.- Juvenile Polyposis.- BLM Mutation and Colorectal Cancer Susceptibility.- The Role of p53 in Colorectal Cancer.- Chromosomes 8q24 and 9p24: Associations with Colorectal Cancer.- Germline Susceptibility – Gene-Environment Interactions.- Genetic Variability in Folate-Mediated One-Carbon Metabolism and Risk of Colorectal Neoplasia.- Genetic Variability in NSAID Targets and NSAID-Metabolizing Enzymes and Colorectal Neoplasia.- The Role of Chemical Carcinogens and Their Biotransformation in Colorectal Cancer.- Calcium and Vitamin D.

Textul de pe ultima copertă

The last 20 years have seen a remarkable increase in knowledge of the etiology of colorectal cancer. At least three aspects are much clearer. First, known environmental agents and behaviors have been identified that increase risk (for example, diets high in meat, obesity, and smoking ) or decrease risk (for example, diets high in plant foods, aspirin, and physical activity) of colorectal cancer. Second, germline mutations in specific genes have been identified for the major inherited syndromes involving colorectal cancer (FAP, Lynch Syndrome, Juvenile Polyposis, MYH-Associated Polyposis, Li-Fraumeni Syndrome) as have variants of genes that modify the risk associated with the known environmental agents. Third, the specific tissue, cellular, and molecular disturbances that characterize the progression to different subtypes of colorectal cancer have been recently described. Genetics of Colorectal Cancer provides the most up-to-date information in each of these areas.

Caracteristici

Will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers Includes supplementary material: sn.pub/extras