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Genomic and Molecular Cardiovascular Medicine: Genomic and Precision Medicine in Clinical Practice

Editat de Dhavendra Kumar, Arthur A.M. Wilde, Perry Mark Elliott
en Limba Engleză Paperback – 20 iun 2024
The Genomic and Molecular Cardiovascular Medicine largely focuses on pertinent genomic and molecular aspects of cardiovascular medicine relevant to all levels of clinical practice, from primary care to preventive healthcare. The book also focuses on practice applications of translational genomic and molecular developments and advances that impact on cardiovascular system structure and function. Each chapter is evidence-based and comprehensive, with in-depth, cutting-edge knowledge relevant to the practice of clinical cardiology and cardiovascular surgery. The book aims to fill a major gap of knowledge resource focused on genomic and molecular aspects of contemporary cardiovascular medicine and surgery practice.
In view of scientific and technical complexities of the field, the book is written by a team of globally acknowledged experts in respective clinical, investigative, therapeutic and preventive aspects. The current practices within cardiovascular medicine and surgery offer excellent opportunity for genomic and molecular applications to achieve the high order effectiveness with maximum efficiency.


  • Includes clinical applications of genomic and molecular new knowledge, along with advances in the practice of cardiovascular medicine and surgery
  • Provides wide coverage of all major clinical and preventive aspects of clinical cardiology, including multi-disciplinary team care
  • Focuses on targeted gene and molecular therapy in clinical cardiovascular medicine and surgery
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Specificații

ISBN-13: 9780128229514
ISBN-10: 0128229519
Pagini: 460
Ilustrații: 150 illustrations (100 in full color)
Dimensiuni: 191 x 235 x 28 mm
Greutate: 1.23 kg
Editura: ELSEVIER SCIENCE
Seria Genomic and Precision Medicine in Clinical Practice


Public țintă

Students & Trainees in General Medicine, Cardiology, Cardiovascular surgery, Pathology, Preventive & Public health Practicing clinical cardiologists and cardiac surgeons, Academic cardiologists and cardiac surgeons Investigators in cardiovascular science, Practitioners & professionals in cardiovascular preventive and public health

Cuprins

1. Introduction to genomic and molecular biology
2. Methods in genomic and molecular medicine
3. Structure and function of the cardiovascular system
4. Molecular embryology of the cardiovascular system
5. Molecular mechanisms of cardiac electrical generation, conduction and regulation
6. Ion channel genomics and proteomics
7. Molecular structure and function of the myocardium
8. Molecular correlations of the myocardium with skeletal and smooth muscles
9. Genetic and molecular basis of metabolic and nutritional cardiovascular regulation
10. Genetic and molecular pathophysiology of heart failure
11. Molecular aspects of arterial, venous and lymphatic circulation
12. Molecular mechanisms and pathophysiology of pulmonary arterial and venous hypertension
13. Molecular perspectives of the cardiovascular inflammation
14. Molecular mechanisms of cardiovascular system response to hyperlipidemia and hyperglycemia
15. Molecular pathology of coronary (ischemic) artery disease (CAD)
16. Molecular basis of the adverse drug and toxin response of the cardiovascular system
17. Precision and personalise cardiovascular medicine including Molecular cardiovascular therapeutics
18. Novel cellular and molecular cardiovascular therapeutics
19. Genomic and Molecular basis of cardiovascular phenotype ontology
20. Preventive and public health applications of the genomic and molecular cardiovascular medicine (including social, ethical and legal aspects)
21. Glossary- selection and explanation of pertinent terms & phrases

Recenzii

*4 stars* "...a multi-authored reference text on application of biomaterials in the treatment of cardiovascular diseases.... [C]ompiles information from clinical reviews and experimental trials to address the vital role that biomaterials play in modern therapies for cardiovascular diseases (CVD). This compilation details the applications of various materials in the context of specific cardiovascular structural and electrophysiological pathologies, highlighting potential limitations alongside potential future applications.... This book effectively bridges the gap between disciplines, offering enough background and context for non-clinicians to grasp the clinical applications and for non-engineers to understand the material and engineering aspects. It presents a unique intersection of fields, delivering a comprehensive analysis of the evolution and expansion of biomedical therapies. Additionally, the book inspires forward-thinking on how future innovations in biomedical materials could further enhance the treatment of cardiovascular diseases." --©Doody’s Review Service, 2024, Manar Jbara, MD (East Tennessee State University Quillen College of Medicine)